| Gene Symbol |
ONECUT1
|
| Entrez Gene |
3175
|
| Alt Symbol |
HNF-6, HNF6, HNF6A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
one cut homeobox 1
|
| Other Description |
hepatocyte nuclear factor 6|hepatocyte nuclear factor 6, alpha|one cut domain family member 1
|
| Swissprots |
Q9UMR6 B2RTV4 Q9UBC0 Q99744
|
| Accessions |
AAD02033 CAB50769 EAW77461 Q9UBC0 AA699732 BC140830 AAI40831 BP289459 BX118406 EU532019 ACB30402 U77975 AAB61705 U96173 AAD00826 XM_011521482 XP_011519784 XM_011521483 XP_011519785 XM_011521484 XP_011519786 XM_011521485 XP_011519787 XM_011521486 XP_011519788 XM_011521487 XP_011519789 XR_931800 XR_931801 XR_931802 XR_931803 NM_004498 NP_004489 NR_073510
|
| Function |
Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Highly expressed in liver; lower expression in testis and skin.
|
| Top Pathways |
Maturity onset diabetes of the young, Signaling pathways regulating pluripotency of stem cells
|