| Gene Symbol | IDH2 |
|---|---|
| Entrez Gene | 3418 |
| Alt Symbol | D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH |
| Species | Human |
| Gene Type | protein-coding |
| Description | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| Other Description | NADP(+)-specific ICDH|isocitrate dehydrogenase [NADP], mitochondrial|oxalosuccinate decarboxylase |
| Swissprots | B4DFL2 B2R6L6 P48735 Q96GT3 |
| Accessions | CBN62262 CBN63691 EAX02082 EAX02083 P48735 AK222916 BAD96636 AK294148 BAG57473 AK299987 BAG61808 AK312627 BAG35513 AK316388 BAH14759 BC009244 AAH09244 BC071828 AAH71828 DQ892817 ABM83743 DQ896063 ABM87062 HY010337 X69433 CAA49208 NM_001289910 NP_001276839 NM_001290114 NP_001277043 NM_002168 NP_002159 |
| Function | Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. |
| Subcellular Location | Mitochondrion. |
| Top Pathways | Citrate cycle (TCA cycle), Peroxisome, Glutathione metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism |