| Gene Symbol |
IDH2
|
| Entrez Gene |
3418
|
| Alt Symbol |
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
isocitrate dehydrogenase 2 (NADP+), mitochondrial
|
| Other Description |
NADP(+)-specific ICDH|isocitrate dehydrogenase [NADP], mitochondrial|oxalosuccinate decarboxylase
|
| Swissprots |
B4DFL2 B2R6L6 P48735 Q96GT3
|
| Accessions |
CBN62262 CBN63691 EAX02082 EAX02083 P48735 AK222916 BAD96636 AK294148 BAG57473 AK299987 BAG61808 AK312627 BAG35513 AK316388 BAH14759 BC009244 AAH09244 BC071828 AAH71828 DQ892817 ABM83743 DQ896063 ABM87062 HY010337 X69433 CAA49208 NM_001289910 NP_001276839 NM_001290114 NP_001277043 NM_002168 NP_002159
|
| Function |
Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
Citrate cycle (TCA cycle), Peroxisome, Glutathione metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism
|
![Western Blot: IDH2 Overexpression Lysate (Adult Normal) [NBL1-11818] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IDH2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1043_IDH2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11818-img0002.jpg)