Gene Symbol |
Cnot11
|
Entrez Gene |
363221
|
Alt Symbol |
RGD1560909
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
CCR4-NOT transcription complex, subunit 11
|
Other Description |
CCR4-NOT transcription complex subunit 11|UPF0760 protein C2orf29 homolog
|
Swissprots |
B0BNA9
|
Accessions |
B0BNA9 EDL99194 EDL99195 BC158750 AAI58751 FQ233266 NM_001108794 NP_001102264
|
Function |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|