Gene Symbol | Sftpd |
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Entrez Gene | 25350 |
Alt Symbol | SP-D, SPD |
Species | Rat |
Gene Type | protein-coding |
Description | surfactant protein D |
Other Description | CP4|PSP-D|lung surfactant protein D|pulmonary surfactant protein D|pulmonary surfactant-associated protein D|surfactant associated protein D|surfactant, pulmonary-associated protein D |
Swissprots | P35248 |
Accessions | EDL90867 P35248 BC070507 AAH70507 M81231 AAA42170 XM_008771065 XP_008769287 NM_012878 NP_037010 |
Function | Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. |
Top Pathways | Phagosome |
CompoZr® Knockout ZFN Kit - CKOZFN62694 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND62694 from Sigma-Aldrich
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SFTPD siRNA (Rat) - CRR0605 from Cohesion Biosciences
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SFTPD - MBS8221894 from MyBioSource
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shRNA set against Rat SFTPD (NM_012878.2) - SHH406096 from Creative biogene
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Rat SFTPD siRNA - orb295454 from Biorbyt
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SFTPD shRNA Plasmid (Rat) - CHR0605 from Cohesion Biosciences
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