FYB

Gene Symbol	FYB
Entrez Gene	2533
Alt Symbol	ADAP, PRO0823, SLAP-130, SLAP130
Species	Human
Gene Type	protein-coding
Description	FYN binding protein
Other Description	FYB-120/130|FYN-T-binding protein|FYN-binding protein|SLP-76-associated phosphoprotein|adhesion and degranulation-promoting adaptor protein|p120/p130
Swissprots	E9PBV9 B4DLN2 O00359 A8K2Y8 O15117 Q9NZI9
Accessions	EAW55981 EAW55982 EAW55983 EAW55984 EAW55985 O15117 AF001862 AAB62226 AF116653 AAF71073 AF198052 AAF62400 AI961953 AK123918 AK130159 AK290403 BAF83092 AK297077 BAG59594 AV761195 BC015933 AAH15933 BC017775 BC058827 BC117449 AAI17450 BC143645 AAI43646 BP265190 BQ015514 BX647195 BX647196 CD691549 CD701507 U93049 AAC51300 XM_006714464 XP_006714527 XM_006714465 XP_006714528 XM_006714466 XP_006714529 XM_011514008 XP_011512310 XM_011514009 XP_011512311 XM_011514010 XP_011512312 XM_011514011 XP_011512313 XM_011514012 XP_011512314 XM_011514013 XP_011512315 NM_001243093 NP_001230022 NM_001465 NP_001456 NM_199335 NP_955367
Function	Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. {ECO:0000269|PubMed:10747096, ECO:0000269|PubMed:15849195, ECO:0000269|PubMed:16980616}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9671755}. Nucleus {ECO:0000250}.
Tissue Specificity	Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
Top Pathways	Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ADAP / FYB Antibody Blocking Peptide - LS-E1568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADAP / FYB Antibody Blocking Peptide - LS-E30368 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAP / FYB Antibody Blocking Peptide - LS-E30369 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADAP / FYB Antibody Blocking Peptide - LS-E23146 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADAP / FYB Antibody Blocking Peptide - LS-E23147 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADAP / FYB Antibody Blocking Peptide - LS-E26567 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FYB/ADAP/SLAP130 Blocking Peptide - NBP1-76811PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

FYB/ADAP/SLAP130 Blocking Peptide - NBP1-76810PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

FYB-Antibody-C-term-Blocking-peptide - BP12307b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FYB Blocking Peptide - abx062642 from Abbexa Category Peptide Species Human

FYB Peptide - AC21-2809-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FYN-binding protein Control Peptide - AP30019CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

FYN-binding protein Control Peptide - AP30020CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ADAP Peptide - 4279P from ProSci Category Peptide Species Human

ADAP Peptide - 4277P from ProSci Category Peptide Species Human

FYB Blocking Peptide - CBP1448 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Recombinant Human FYN-binding protein(FYB) - CSB-YP009099HU CSB-EP009099HU CSB-BP009099HU CSB-MP009099HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FYN-binding protein (transcript variant 1) - TP314537 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FYN-binding protein (transcript variant 2) - TP320537 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FYB, Peptide - MBS427962 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog, Bovine

FYB/ADAP/SLAP130 Recombinant Protein Antigen - NBP1-91916PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FYB Peptide, Human - M34GP05981H from Creative Peptides Category Peptide Source Synthetic. Species Human

FYN-binding protein (FYB), Recombinant Protein - MBS1073353 from MyBioSource Category Protein Prices $1,600.00, $1,600.00, $1,830.00, $1,830.00, $2,745.00, $2,745.00, $3,210.00, $3,210.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

FYB peptide - orb217311 from Biorbyt Category Peptide Species Human

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