CD247

Gene Symbol CD247
Entrez Gene 919
Alt Symbol CD3-ZETA, CD3H, CD3Q, CD3Z, IMD25, T3Z, TCRZ
Species Human
Gene Type protein-coding
Description CD247 molecule
Other Description CD247 antigen, zeta subunit|CD3Z antigen, zeta polypeptide (TiT3 complex)|CD3zeta chain|T-cell antigen receptor complex, zeta subunit of CD3|T-cell receptor T3 zeta chain|T-cell surface glycoprotein CD3 zeta chain|TCR zeta chain
Swissprots B1AK49 Q8TAX4 Q5VX13 P20963
Accessions A46461 AAB22030 AAB24602 AAY57330 EAW90790 EAW90791 EAW90792 P20963 AF228312 AAF34793 AI420774 AK128376 BAC87407 AK223325 BAD97045 AK313946 BAG36664 AL557555 BC025703 AAH25703 BI819937 DQ893778 ABM84704 EF079882 EF364117 EF364118 EF364119 ABQ28690 EU117371 ABW06577 EU117372 ABW06578 EU117373 ABW06579 EU118788 ABW96174 EU118789 ABW96175 EU118790 ABW96176 EU118791 ABW96177 EU118792 ABW96178 EU118793 ABW96179 EU176191 ABW03642 EU597245 ACC61185 J04132 AAA60394 X55510 X55511 X55512 XM_011510144 XP_011508446 XM_011510145 XP_011508447 NM_000734 NP_000725 NM_198053 NP_932170
Function Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Chagas disease (American trypanosomiasis)