DCTPP1

Gene Symbol DCTPP1
Entrez Gene 79077
Alt Symbol CDA03, RS21C6, XTP3TPA
Species Human
Gene Type protein-coding
Description dCTP pyrophosphatase 1
Other Description XTP3-transactivated gene A protein|XTP3-transactivated protein A|dCTPase 1|deoxycytidine-triphosphatase 1
Swissprots Q9H773
Accessions EAW52247 Q9H773 AF210430 AAK48422 AF212242 AAK14927 AK024843 BAB15025 AY453409 AAR26724 BC001344 AAH01344 CR457335 CAG33616 NM_024096 NP_077001
Function Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non- canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Pyrimidine metabolism

XTP3TPA-Over-expression-Lysate - LY11305a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag XTP3TPA (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the XTP3TPA gene

XTP3TPA 293T Cell Transient Overexpression Lysate(Denatured) - H00079077-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

DCTPP1 overexpression lysate - LY411367 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

DCTPP1 293 Cell Lysate - 405705 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

XTP3TPA Overexpression Lysate (Native) - NBL1-17921 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: XTP3TPA Overexpression Lysate (Adult Normal) [NBL1-17921] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for XTP3TPA.

DCTPP1 Over-expression Lysate Product - GWB-641F86 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

XTP3TPA Overexpression Lysate (Denatured) - H00079077-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human DCTPP1 Knockdown Stable Cell Line - CSC-DC004105 from Creative biogene

Category Cell Line
Species Human

DCTPP1 KO Cell Lysate-HEK293T - CLKO-0852 from Creative biogene

Category Cell Lysate
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