HSD11B2

Gene Symbol HSD11B2
Entrez Gene 3291
Alt Symbol AME, AME1, HSD11K, HSD2, SDR9C3
Species Human
Gene Type protein-coding
Description hydroxysteroid (11-beta) dehydrogenase 2
Other Description -HSD11 type II|11-DH2|11-beta-HSD2|11-beta-hydroxysteroid dehydrogenase type 2|11-beta-hydroxysteroid dehydrogenase type II|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase isozyme 2|short chain dehydrogenase/reductase family 9C member 3
Swissprots Q9UCW8 Q9UC50 Q8N439 Q9UCW6 A7LB28 P80365 Q9UCW5 C5HTY7 Q9UCW7 Q13194 Q96QN8 Q9UC51 Q6P2G9
Accessions AAB48544 AAD14324 AAK91586 ABS29267 ACS13714 EAW83134 P80365 BC036780 AAH36780 BC064536 AAH64536 U14631 AAA91969 U26726 AAC50356 NM_000196 NP_000187
Function Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Subcellular Location Microsome {ECO:0000269|PubMed:17314322}. Endoplasmic reticulum {ECO:0000269|PubMed:17314322}.
Tissue Specificity Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.
Top Pathways Steroid hormone biosynthesis, Aldosterone-regulated sodium reabsorption

11β-HSD2 (H-145) - sc-20176 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
11β-HSD2 (H-145): sc-20176. Western blot analysis of 11β-HSD2 expression in non-transfected 293T: sc-117752 (A), human 11β-HSD2 transfected 293T: sc-116955 (B) and HeLa (C) whole cell lysates.

11β-HSD2 (C-17) - sc-19263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
11β-HSD2 (C-17): sc-19263. Western blot analysis of 11β-HSD2 expression in non-transfected: sc-117752 (A) and human 11β-HSD2 transfected: sc-116955 (B) 293T whole cell lysates.

11β-HSD2 (T-12) - sc-19262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
11β-HSD2 (T-12): sc-19262. Western blot analysis of 11β-HSD2 expression in non-transfected: sc-117752 (A) and human 11β-HSD2 transfected: sc-116955 (B) 293T whole cell lysates.

Anti-HSD11B2 antibody - ab103031 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD11B2 antibody (ab103031) at 1/100 dilution + MCF-7 cell line lysates at 35 µg

Anti-HSD11B2 antibody - ab89669 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-HSD11B2 antibody (ab89669) at 1 µg/ml + human colon tissue lysate at 50 µg

Anti-HSD11B2 antibody - Azide free - ab37800 from Abcam

Prices $378.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-HSD11B2 antibody - Azide free (ab37800) at 1/2000 dilution + E. coli derived fusion proteinSecondaryHRP conjugated Goat anti IgY at 1/1000 dilution

Anti-HSD2 / HSD11B2 Antibody (aa277-306) IHC-plus™ - LS-B10555 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-HSD2 / HSD11B2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10555 dilution 1:100.

Anti-HSD2 / HSD11B2 Antibody (aa25-40) IHC-plus™ - LS-B2135 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD11B2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2135 concentration 10 ug/ml.

Anti-HSD2 / HSD11B2 Antibody (C-Terminus) - LS-C24599 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (C-Terminus) - LS-C24601 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (C-Terminus) - LS-C24602 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (C-Terminus) - LS-C24605 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (C-Terminus) - LS-C24606 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, AP) - LS-C207119 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, Biotin) - LS-C207123 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, APC) - LS-C207120 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, FITC) - LS-C207125 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, Azide-free, HRP) - LS-C207127 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody (aa277-306, PE) - LS-C207129 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody - LS-C310666 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody - LS-C308319 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody - LS-C310669 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD2 / HSD11B2 Antibody - LS-C150690 from LifeSpan Bioscience

Prices $325.00
Sizes 1 ea
Host Rabbit
Clonality Polyclonal
Western blot of HSD2 / HSD11B2 antibody LS-C150690.

Anti-HSD2 / HSD11B2 Antibody (N-Terminus) - LS-C80413 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

HSD11B2 Antibody - NBP1-53163 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HSD11B2 Antibody [NBP1-53163] - Human Muscle lysate, concentration 0.2-1 ug/ml.
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