DPM1

Gene Symbol DPM1
Entrez Gene 8813
Alt Symbol CDGIE, MPDS
Species Human
Gene Type protein-coding
Description dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
Other Description DPM synthase complex, catalytic subunit|DPM synthase subunit 1|MPD synthase subunit 1|dolichol monophosphate mannose synthase|dolichol-phosphate mannose synthase subunit 1|dolichol-phosphate mannosyltransferase subunit 1|dolichyl-phosphate beta-D-mannosyltransferase subunit 1|mannose-P-dolichol synthase subunit 1
Swissprots Q6IB78 O15157 O60762 Q96HK0
Accessions BAA25647 EAW75607 EAW75608 EAW75609 O60762 AF007875 AAC98797 AK289569 BAF82258 BC007073 AAH07073 BC008427 BC008466 AAH08466 BC016322 AAH16322 CR456926 CAG33207 D86198 BAA25646 HQ447146 ADQ31633 XM_005260600 XP_005260657 XM_005260601 XP_005260658 XM_011529093 XP_011527395 XM_011529094 XP_011527396 XR_244156 NM_003859 NP_003850
Function Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins; catalytic subunit of the dolichol- phosphate mannose (DPM) synthase complex.
Subcellular Location Endoplasmic reticulum.
Top Pathways N-Glycan biosynthesis