| Gene Symbol |
DPM1
|
| Entrez Gene |
8813
|
| Alt Symbol |
CDGIE, MPDS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
|
| Other Description |
DPM synthase complex, catalytic subunit|DPM synthase subunit 1|MPD synthase subunit 1|dolichol monophosphate mannose synthase|dolichol-phosphate mannose synthase subunit 1|dolichol-phosphate mannosyltransferase subunit 1|dolichyl-phosphate beta-D-mannosyltransferase subunit 1|mannose-P-dolichol synthase subunit 1
|
| Swissprots |
Q6IB78 O15157 O60762 Q96HK0
|
| Accessions |
BAA25647 EAW75607 EAW75608 EAW75609 O60762 AF007875 AAC98797 AK289569 BAF82258 BC007073 AAH07073 BC008427 BC008466 AAH08466 BC016322 AAH16322 CR456926 CAG33207 D86198 BAA25646 HQ447146 ADQ31633 XM_005260600 XP_005260657 XM_005260601 XP_005260658 XM_011529093 XP_011527395 XM_011529094 XP_011527396 XR_244156 NM_003859 NP_003850
|
| Function |
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins; catalytic subunit of the dolichol- phosphate mannose (DPM) synthase complex.
|
| Subcellular Location |
Endoplasmic reticulum.
|
| Top Pathways |
N-Glycan biosynthesis
|
![Western Blot: DPM1 Overexpression Lysate (Adult Normal) [NBL1-09992] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DPM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8490_DPM1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09992-img0002.jpg)