| Gene Symbol |
St13
|
| Entrez Gene |
81800
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
suppression of tumorigenicity 13
|
| Other Description |
hip|hsc70-interacting protein|protein ST13 homolog|suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein
|
| Swissprots |
P50503
|
| Accessions |
EDM15726 P50503 BC078804 AAH78804 FQ212434 FQ228746 X82021 CAA57546 NM_031122 NP_112384
|
| Function |
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins. {ECO:0000269|PubMed:7585962}.
|
| Subcellular Location |
Cytoplasm.
|
