Gene Symbol | ITGA10 |
---|---|
Entrez Gene | 8515 |
Alt Symbol | PRO827 |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha 10 |
Other Description | integrin alpha-10 |
Swissprots | O75578 Q6UXJ6 Q9UHZ8 B2RTV5 B2RAM4 |
Accessions | AAF61638 EAW71424 EAW71425 O75578 AF074015 AAC31952 AF112345 AAF21944 AK304155 BAG65044 AK304183 BAG65063 AK314255 BAG36921 AY358325 AAQ88691 BC140831 AAI40832 BC144637 AAI44638 BC160008 AAI60008 BM311010 XM_005277436 XP_005277493 XM_011510079 XP_011508381 XM_011510080 XP_011508382 XM_011510081 XP_011508383 XM_011510082 XP_011508384 XM_011510083 XP_011508385 XM_011510084 XP_011508386 XR_921987 XR_921988 XR_921989 XR_921990 NM_001303040 NP_001289969 NM_001303041 NP_001289970 NM_003637 NP_003628 |
Function | Integrin alpha-10/beta-1 is a receptor for collagen. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Widely expressed with highest expression in muscle and heart. Found in articular cartilage. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |