| Gene Symbol |
MOV10
|
| Entrez Gene |
4343
|
| Alt Symbol |
fSAP113, gb110
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Mov10 RISC complex RNA helicase
|
| Other Description |
Mov10, Moloney leukemia virus 10, homolog|functional spliceosome-associated protein 113|moloney leukemia virus 10 protein|putative helicase MOV-10
|
| Swissprots |
Q5JR03 Q8TEF0 Q9HCE1 Q9BUJ9 Q9BSY3
|
| Accessions |
CAE89762 EAW56528 EAW56529 EAW56530 EAW56531 Q9HCE1 AB046851 BAB13457 AK023297 BAB14514 AK057353 BAG51905 AK074174 BAB85000 AK226011 AK301229 BAH13436 AK308874 AK310512 AL832805 AL833353 AM393007 CAL37885 AM393678 CAL38554 BC002548 AAH02548 BC004499 AAH04499 BC009312 AAH09312 BC025339 BU623853 BX647787 DB066263 DQ892188 ABM83114 DQ896845 ABM87844 XM_005270868 XP_005270925 XM_005270869 XP_005270926 XM_005270870 XP_005270927 XM_006710644 XP_006710707 XR_426609 XR_946657 NM_001130079 NP_001123551 NM_001286072 NP_001273001 NM_020963 NP_066014
|
| Function |
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. {ECO:0000269|PubMed:16289642, ECO:0000269|PubMed:17507929, ECO:0000269|PubMed:18552826, ECO:0000269|PubMed:22791714}.
|
| Subcellular Location |
Cytoplasm, P-body {ECO:0000269|PubMed:16289642}.
|