PFKL

Gene Symbol PFKL
Entrez Gene 5211
Alt Symbol ATP-PFK, PFK-B, PFK-L
Species Human
Gene Type protein-coding
Description phosphofructokinase, liver
Other Description 6-phosphofructokinase type B|6-phosphofructokinase, liver type|ATP-PFK|ATP-dependent 6-phosphofructokinase, liver type|liver-type 1-phosphofructokinase|phosphofructo-1-kinase isozyme B|phosphohexokinase
Swissprots Q96IH4 P17858 Q9BR91 Q96A64
Accessions BAA95561 CAB46744 EAX09439 EAX09440 P17858 AB209127 BAD92364 AF086180 AK054735 BAG51419 AK091488 AK098228 AK303605 BAG64620 AK308437 BC004920 AAH04920 BC006422 AAH06422 BC007536 AAH07536 BC008964 AAH08964 BC009919 AAH09919 BC018295 AAH18295 BG390460 BQ067366 BU177678 BX351711 BX537446 CAD97688 BX641051 CAE46026 CA449348 CB997055 DQ893435 ABM84361 DQ896792 ABM87791 HY111158 X15573 CAA33597 XM_005261135 XP_005261192 XM_005261136 XP_005261193 XM_005261137 XP_005261194 XM_006724011 XP_006724074 XM_006724012 XP_006724075 XM_011529602 XP_011527904 XM_011529603 XP_011527905 NM_001002021 NP_001002021 NM_002626 NP_002617
Function Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. {ECO:0000255|HAMAP-Rule:MF_03184, ECO:0000269|PubMed:22923583}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}.
Top Pathways RNA degradation, Pentose phosphate pathway, AMPK signaling pathway, Central carbon metabolism in cancer, Glucagon signaling pathway

PFKL Antibody - 8175 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PFKL Antibody.

PFKL (A-6) - sc-393713 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PFKL (A-6): sc-393713. Western blot analysis of PFKL expression in HeLa (A), Hep G2 (B), SK-BR-3 (C), A-431 (D) and LNCaP (E) whole cell lysates.

PFKL (C-22) - sc-130226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PFKL (C-22): sc-130226. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

PFKL (H-36) - sc-292523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PFKL (H-36): sc-292523. Western blot analysis of PFKL expression in Hep G2 (A) and HeLa (B) whole cell lysates.

PFKL (YT4) - sc-100542 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PFKL (YT4): sc-100542. Western blot analysis of PFKL expression in HeLa whole cell lysate.

Anti-PFKL antibody - ab37583 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKL antibody (ab37583) at 1/100 dilution + HepG2 cell lysate

Anti-PFKL antibody - ab65066 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PFKL antibody (ab65066) at 1/500 dilutionLane 1 : extracts from A549 cellsLane 2 : extracts from NIH-3T3 cellsLane 3 : extracts from NIH-3T3 cells with immunizing peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-PFKL antibody - ab55610 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PFKL antibody - ab172090 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PFKL antibody (ab172090) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with PFKLLane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.

Anti-PFKL antibody [EPR11904] - ab181064 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11904
All lanes : Anti-PFKL antibody [EPR11904] (ab181064) at 1/5000 dilutionLane 1 : HepG2 cell lysateLane 2 : A431 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-PFKL Antibody (aa442-491) - LS-C80772 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

Anti-PFKL Antibody (aa691-740) - LS-C118803 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from A549/NIH-3T3 cells, using K6PL Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PFKL Antibody (clone 2A9) - LS-C197885 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A9
PFKL monoclonal antibody (M03), clone 2A9 Western Blot analysis of PFKL expression in HeLa.

Anti-PFKL Antibody (C-Terminus, AP) - LS-C226113 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (C-Terminus, Biotin) - LS-C226115 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (C-Terminus, APC) - LS-C226114 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (C-Terminus, FITC) - LS-C226116 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKP Antibody (Gln365) - LS-C176921 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PFK-1 (Q365) pAb in extracts from A549 and raw264.7 cell.

Anti-PFKL Antibody (C-Terminus, PE) - LS-C226117 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (C-Terminus) - LS-C328212 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (aa669-699) - LS-C101261 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-PFKL Antibody (aa730-780) - LS-C290963 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKL Antibody (Glu724) - LS-C176741 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of PFK-B (E724) pAb in paraffin-embedded human brain tissue.

Anti-PFKFB1 Antibody (Glu442) - LS-C176899 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of PFK-2 liv (E442) pAb in paraffin-embedded human liver carcinoma tissue.

Anti-PFKL Antibody (aa1-50) - LS-C290960 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PFKL by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-PFKL antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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