ACTN1

Gene Symbol	ACTN1
Entrez Gene	87
Alt Symbol	BDPLT15
Species	Human
Gene Type	protein-coding
Description	actinin, alpha 1
Other Description	F-actin cross-linking protein|actinin 1 smooth muscle|alpha-actinin cytoskeletal isoform|alpha-actinin-1|non-muscle alpha-actinin-1
Swissprots	Q1HE25 P12814 B4DHH3 B7TY16 B3V8S3 Q9BTN1
Accessions	EAW80971 EAW80972 EAW80973 EAW80974 EAW80975 EAW80976 P12814 AJ844628 CAH59747 AK098203 BAG53591 AK124378 AK225782 AK294317 BAG57591 AK295099 BAG58135 AK298496 BAH12801 AK299362 BAG61357 BC003576 AAH03576 BC004984 BC011987 BC015766 AAH15766 BC127124 AAI27125 BI494856 BT007207 AAP35871 BX248020 CAD62344 BX641076 DC321454 DC372566 DQ496098 ABF50047 DQ890778 ABM81704 DQ895768 ABM86694 EU716325 ACE62922 FJ410030 ACJ24535 M95178 AAA51582 X15804 CAA33803 X55187 CAA38970 XM_011537265 XP_011535567 XM_011537266 XP_011535568 XM_011537267 XP_011535569 XM_011537268 XP_011535570 XM_011537269 XP_011535571 XM_011537270 XP_011535572 XM_011537271 XP_011535573 NM_001102 NP_001093 NM_001130004 NP_001123476 NM_001130005 NP_001123477
Function	F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24069336, ECO:0000269|PubMed:7750553}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:7750553}. Cell membrane {ECO:0000250}. Cell junction {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and central reticular structures (By similarity). {ECO:0000250}.
Top Pathways	Systemic lupus erythematosus, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Leukocyte transendothelial migration, Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Chicken alpha Actinin full length protein - ab73633 from Abcam Category Protein Source Native Species Chicken

Human alpha Actinin full length protein - ab152166 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human alpha Actinin protein fragment - ab152167 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ACTN1 Antibody Blocking Peptide - LS-E21361 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACTN1 Antibody Blocking Peptide - LS-E9611 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human alpha-Actinin 1 Protein - H00000087-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

alpha-Actinin 1 Partial Recombinant Protein - H00000087-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ACTN1-Antibody-N-term-Blocking-Peptide - BP8512a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

alpha Actinin 1 Blocking Peptide - 33R-1985 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Alpha-actinin-1 / ACTN1 - H00000087-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Alpha-actinin-1 / ACTN1 - H00000087-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Alpha-actinin-1 / ACTN1 - H00000087-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Alpha-actinin-1 / ACTN1 - H00000087-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

a-Actinin fusion protein - Ag1859 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

a-Actinin - PRPS-525 from NeoScientific Category Protein Prices $65.00, $169.00, $3,250.00 Sizes 10 µg, 50 µg, 1 mg Source Chicken Gizzard.

Actinin Alpha Protein - BP000474-PRO-518 from Syd Labs Category Protein Prices $160.00, $2,500.00 Sizes 50 µg, 1 mg Source Chicken Gizzard-derived.

Recombinant Human ACTN1, GST-tagged - ACTN1-9339H from Creative Biomart Category Protein Source E.coli Species Human

ACTN1/2/3/4 Blocking Peptide - CBP3466 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

Actinin-α1/2/3/4 (W48) Peptide - BS2206P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Alpha-actinin-1(ACTN1) ,partial - CSB-YP001241HU CSB-EP001241HU CSB-BP001241HU CSB-MP001241HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACTN1, 1-249aa, Human, His tag, E.coli - ATGP3162 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ACTN1 protein - 80R-4307 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Alpha-actinin-1 / ACTN1 (transcript variant 2) - TP304924 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Alpha-actinin-1(ACTN1) ,partial, Recombinant Protein - MBS959794 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ACTN1, Peptide - MBS428403 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

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