| Gene Symbol | Cxcr1 |
|---|---|
| Entrez Gene | 54258 |
| Alt Symbol | Il8ra |
| Species | Rat |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) receptor 1 |
| Other Description | C-X-C chemokine receptor type 1|CXC-R1|CXCR-1|IL-8R A|high affinity interleukin-8 receptor A|interleukin 8 receptor, alpha |
| Swissprots | P70612 |
| Accessions | AAC52962 EDL75336 P70612 XM_006245273 XP_006245335 NM_019310 NP_062183 |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Top Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Chemokine signaling pathway |