TPK1

Gene Symbol TPK1
Entrez Gene 27010
Alt Symbol HTPK1, PP20, THMD5
Species Human
Gene Type protein-coding
Description thiamin pyrophosphokinase 1
Other Description placental protein 20|thiamine diphosphokinase|thiamine kinase
Swissprots Q9H602 I6L9B8 A8K0T7 Q6NUR5 Q9H3S4 D3DWG0
Accessions AAS00370 EAL24415 EAW80091 EAW80092 Q9H3S4 AB028138 BAB20326 AF297710 AAK01351 AK021810 AK026374 BAB15465 AK091736 BAG52408 AK128661 BAC87556 AK130640 AK289652 BAF82341 AK308693 AY206415 AAO38775 BC014552 BC040555 AAH40555 BC068460 AAH68460 BI770816 BX446289 CR749248 CAH18104 DA135998 XM_005249970 XP_005250027 XM_006715925 XP_006715988 XM_011516031 XP_011514333 XM_011516032 XP_011514334 XM_011516033 XP_011514335 XM_011516034 XP_011514336 XM_011516035 XP_011514337 XM_011516036 XP_011514338 XM_011516037 XP_011514339 XM_011516038 XP_011514340 XM_011516039 XP_011514341 XM_011516040 XP_011514342 XM_011516041 XP_011514343 XM_011516042 XP_011514344 XM_011516043 XP_011514345 XM_011516044 XP_011514346 XM_011516045 XP_011514347 XM_011516046 XP_011514348 XM_011516047 XP_011514349 XM_011516048 XP_011514350 XM_011516049 XP_011514351 XM_011516050 XP_011514352 XR_927446 XR_927448 XR_927450 XR_927451 XR_927453 NM_001042482 NP_001035947 NM_022445 NP_071890
Function Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate. {ECO:0000269|PubMed:11342111}.
Tissue Specificity Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. {ECO:0000269|PubMed:11342111, ECO:0000269|PubMed:11342117}.
Top Pathways Thiamine metabolism

Human TPK1 full length protein - ab123150 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab123150 at approximately 29.8kDa (3µg).

Human TPK1 full length protein - ab200487 from Abcam

Category Protein
Source E. coli
Species Human
DTT reduced SDS-PAGE analysis of ab200487 with staining overnight with Coomassie Blue. DTT-reduced protein migrates as 28 kDa.

TPK1 Antibody Blocking Peptide - LS-E9965 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TPK1 Antibody Blocking Peptide - LS-E20008 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TPK1 Partial Recombinant Protein - H00027010-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 2 µg
Species Human

TPK1 Recombinant Protein - H00027010-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human TPK1 Protein - NBP1-99102 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human

TPK1-Antibody-N-term-Blocking-Peptide - BP9142a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human TPK1 protein - orb169464 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Source E. coli

TPK1 Blocking Peptide - 33R-9983 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

TPK1 protein (His tag) - 80R-2159 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

Thiamine pyrophosphokinase 1 (TPK1) (1-243, His-tag) - AR50240PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
Thiamine pyrophosphokinase 1 (TPK1)

Thiamine pyrophosphokinase 1 (TPK1) (1-243, His-tag) - AR50240PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
Thiamine pyrophosphokinase 1 (TPK1)

Thiamine pyrophosphokinase 1 (TPK1) - H00027010-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Thiamine pyrophosphokinase 1 (TPK1) - H00027010-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Source in vitro transl.
Species Human

Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Source in vitro transl.
Species Human

TPK1, 1-243aa, Human, His tag, E.coli - 01-P1415 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

TPK1 Recombinant Protein - 96-742 from ProSci

Category Protein
Prices $300.00
Sizes 100 µg
Source E. coli
Species Human
The purity of rh TPK1 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

TPK1 fusion protein - Ag1404 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

TPK1 Human - PKPS-030 from NeoScientific

Category Protein
Prices $65.00, $169.00, $3,510.00
Sizes 5 µg, 20 µg, 1 mg
Source Escherichia Coli.
Species Human

Recombinant Human Thiamin Pyrophosphokinase 1 Enzyme - BP002761-PKA-023 from Syd Labs

Category Protein
Prices $160.00, $2,700.00
Sizes 20 µg, 1 mg
Source E. coli-derived.
Species Human

Recombinant Human TPK1, GST-tagged - TPK1-3369H from Creative Biomart

Category Protein
Source E.coli
Species Human
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