AHCY

Gene Symbol AHCY
Entrez Gene 191
Alt Symbol SAHH, adoHcyase
Species Human
Gene Type protein-coding
Description adenosylhomocysteinase
Other Description S-adenosyl-L-homocysteine hydrolase|S-adenosylhomocysteine hydrolase
Swissprots E1P5P2 F5H737 B3KUN3 Q96A36 P23526 A8K307
Accessions EAW76279 EAW76280 EAW76281 P23526 AK097610 BAG53495 AK290422 BAF83111 AK300014 BAG61829 AK309204 AK316180 BAH14551 BC010018 AAH10018 BC011606 AAH11606 BC114924 AAI14925 BE785593 BT006697 AAP35343 DB043400 DC301059 DC413105 DQ890569 ABM92186 DQ891701 ABM82627 DQ893730 ABM84656 DQ895397 ABM86323 HG511319 M61831 AAA51681 M61832 AAA51682 XM_005260316 XP_005260373 XM_005260317 XP_005260374 XM_011528656 XP_011526958 XM_011528657 XP_011526959 XM_011528658 XP_011526960 XM_011528659 XP_011526961 XM_011528660 XP_011526962 NM_000687 NP_000678 NM_001161766 NP_001155238
Function Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. {ECO:0000269|PubMed:12590576}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways Cysteine and methionine metabolism

SAHH (A-6) - sc-393129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SAHH (A-6): sc-393129. Western blot analysis of SAHH expression in non-transfected 293T: sc-117752 (A), human SAHH transfected 293T: sc-159779 (B), HEL 92.1.7 (C), HeLa (D) and A549 (E) whole cell lysates.

SAHH (A-11) - sc-271389 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SAHH (A-11): sc-271389. Western blot analysis of SAHH expression in A549 (A) and HeLa (B) whole cell lysates.

SAHH (N-20) - sc-55758 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SAHH (N-20): sc-55758. Western blot analysis of SAHH expression in non-transfected: sc-117752 (A) and mouse SAHH transfected: sc-127505 (B) 293T whole cell lysates.

SAHH (F-11) - sc-365070 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SAHH (F-11): sc-365070. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

SAHH (H-75) - sc-292967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SAHH (H-75): sc-292967. Western blot analysis of SAHH expression in Hep G2 whole cell lysate.

SAHH (W-20) - sc-55759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SAHH (W-20): sc-55759. Western blot analysis of SAHH expression in non-transfected: sc-117752 (A) and mouse SAHH transfected: sc-127505 (B) 293T whole cell lysates.

Anti-S adenosylhomocysteine hydrolase antibody - ab187518 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling S adenosylhomocysteine hydrolase with ab187518 at 1/200. Magnification: 200x.

Anti-S adenosylhomocysteine hydrolase antibody - ab54733 from Abcam

Host Mouse
Clonality Monoclonal
Anti-S adenosylhomocysteine hydrolase antibody (ab54733) at 1/500 dilution + A549 cell lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-S adenosylhomocysteine hydrolase antibody - ab54734 from Abcam

Host Mouse
Clonality Monoclonal

Anti-S adenosylhomocysteine hydrolase antibody [EPR9260] - ab151734 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9260
All lanes : Anti-S adenosylhomocysteine hydrolase antibody [EPR9260] (ab151734) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A549 cell lysateLane 3 : HepG2 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-S adenosylhomocysteine hydrolase antibody [EPR9261] - ab134966 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9261
All lanes : Anti-S adenosylhomocysteine hydrolase antibody [EPR9261] (ab134966) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A549 cell lysateLane 3 : HepG2 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-S adenosylhomocysteine hydrolase antibody - Aminoterminal end - ab56146 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-S adenosylhomocysteine hydrolase antibody - Aminoterminal end (ab56146) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-S adenosylhomocysteine hydrolase antibody - N-terminal - ab135518 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-S adenosylhomocysteine hydrolase antibody - N-terminal (ab135518) at 1/50 dilution + 293 cell line lysate at 35 µg

Anti-SAHH / AHCY Antibody - LS-C333964 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human breast cancer using AHCY antibody at dilution of 1:200 (200x lens).

Anti-SAHH / AHCY Antibody (N-Terminus) - LS-C46949 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (aa1-432) - LS-C126646 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (clone 1E11-1A7) - LS-C196630 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1E11-1A7

Anti-SAHH / AHCY Antibody - LS-C306145 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (Biotin) - LS-C317576 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (FITC) - LS-C317577 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (HRP) - LS-C317581 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody - LS-C317582 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SAHH / AHCY Antibody (N-Terminus) - LS-C111328 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AHCY antibody LS-C111328 Western blot of Fetal Liver lysate.

Anti-SAHH / AHCY Antibody (aa136-185) - LS-C146102 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AHCY antibody LS-C146102 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.

Anti-SAHH / AHCY Antibody (Biotin) - LS-C317892 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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