Got1

Gene Symbol	Got1
Entrez Gene	14718
Alt Symbol	AI789014, Got-1, cAspAT, cCAT
Species	Mouse
Gene Type	protein-coding
Description	glutamic-oxaloacetic transaminase 1, soluble
Other Description	aspartate aminotransferase, cytoplasmic|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|cytosolic aspartate aminotransferase|glutamate oxaloacetate transaminase 1, soluble|transaminase A
Swissprots	Q3UJH8 P05201
Accessions	CAA30275 EDL41904 P05201 AK146445 BAE27177 AK147807 AK147934 AK186873 AK192547 AK195432 AK203412 AK212371 AV574373 BC002057 AAH02057 BY441762 CK334037 J02623 AAA37263 XR_386441 NM_010324 NP_034454
Function	Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed in neurons of the retina. Localizes to the inner and outer plexiform layers, the inner and outer nuclear layer and the outer segments of photoreceptors. {ECO:0000269|PubMed:21937432}.
Top Pathways	Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Phenylalanine metabolism, Biosynthesis of amino acids, Tyrosine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GOT1 protein - 80R-4223 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

Mouse AST Protein - abx065467 from Abbexa Category Protein Source E.coli Species Mouse

GOT1 (1-413, His-tag) - AR51905PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Mouse

GOT1 (1-413, His-tag) - AR51905PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Mouse

Aspartate Aminotransferase (AST), Mouse - 20-7544 from ARP American Research Products Category Protein Prices $549.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Got1, His-tagged - Got1-3668M from Creative Biomart Category Protein Source E. Coli or Yeast Species Mouse

Recombinant Mouse Got1, His-tagged - Got1-65M from Creative Biomart Category Protein Source E.coli Species Mouse

Recombinant Aspartate Aminotransferase (AST) - RPB214Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Aspartate Aminotransferase (AST) - RPB214Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Aspartate aminotransferase, cytoplasmic(Got1) - CSB-YP009679MO CSB-EP009679MO CSB-BP009679MO CSB-MP009679MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Got1, 1-413aa, Mouse, His tag, E.coli (Bioactivity Validated) - ATGP3085 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Mouse

Aspartate Aminotransferase (AST), Recombinant Protein - MBS2010629 from MyBioSource Category Protein Prices $260.00, $475.00, $695.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Aspartate aminotransferase, cytoplasmic (Got1) , Recombinant Protein - MBS949713 from MyBioSource Category Protein Prices $1,910.00, $1,910.00, $2,370.00, $2,370.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Recombinant Mouse GOT1 Protein - GOT1-7078M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Recombinant Mouse Aspartate Aminotransferase Protein - NBP2-52088 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 100 µg, 500 µg Source E. coli

Glutamic-Oxaloacetic Transaminase 1, Mouse Recombinant - 228-20817-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Mouse

Got1 - PAT-82946-2 from Nordic BioSite Category Protein Species Mouse

Got1 - PAT-82946-1 from Nordic BioSite Category Protein Species Mouse

Mouse Aspartate Aminotransferase (cAspAT) - PMA33085 from AssayPro Prices $80.00 Sizes 20 µg Source Got1, 1-413 aa, Mouse, His tag, E. coli (Bioactivity Validated) Species Mouse

AST Recombinant Protein (OPCD01510) - OPCD01510 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Glutamic-Oxaloacetic Transaminase 1, Recombinant Protein - MBS140590 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

Got1, Recombinant Protein - MBS206006 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Mouse

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