Gene Symbol | TWSG1 |
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Entrez Gene | 57045 |
Alt Symbol | TSG |
Species | Human |
Gene Type | protein-coding |
Description | twisted gastrulation BMP signaling modulator 1 |
Other Description | twisted gastrulation homolog 1|twisted gastrulation protein homolog 1 |
Swissprots | Q96K46 B2RE08 Q9GZX9 Q8NBI7 D3DUH9 |
Accessions | EAX01606 EAX01607 Q9GZX9 AF196834 AAG43468 AF294628 AAG10076 AI742025 AJ297391 CAC05581 AK027629 BAB55246 AK075550 BAC11693 AK315751 BAG38105 BC020490 AAH20490 BU632669 DA735800 HQ447098 ADQ31585 XM_011525704 XP_011524006 NM_020648 NP_065699 |
Function | May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
twisted gastrulation (V-18) - sc-30453 from Santa Cruz Biotechnology
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Anti-TWSG1 antibody - ab183890 from Abcam
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Anti-TWSG1 antibody - ab57552 from Abcam
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Anti-TSG / TWSG1 Antibody (clone 2F3) IHC-plus⢠- LS-B10447 from LifeSpan Bioscience
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TSG Antibody - NBP1-80660 from Novus Biologicals
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TSG Antibody (2F3) - H00057045-M07 from Novus Biologicals
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TSG Antibody (6E6) - H00057045-M01 from Novus Biologicals
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TSG Antibody - H00057045-A01 from Novus Biologicals
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TWSG1 Polyclonal Antibody - bs-11606R from Bioss
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TWSG1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11606R-A350 from Bioss
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TWSG1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11606R-A488 from Bioss
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TWSG1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11606R-A555 from Bioss
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TWSG1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11606R-A647 from Bioss
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TWSG1 Polyclonal Antibody, Cy3 Conjugated - bs-11606R-Cy3 from Bioss
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TWSG1 Polyclonal Antibody, Cy5 Conjugated - bs-11606R-Cy5 from Bioss
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TWSG1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11606R-Cy5.5 from Bioss
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TWSG1 Polyclonal Antibody, Cy7 Conjugated - bs-11606R-Cy7 from Bioss
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TWSG1 Polyclonal Antibody, FITC Conjugated - bs-11606R-FITC from Bioss
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TWSG1 Polyclonal Antibody, Biotin Conjugated - bs-11606R-Biotin from Bioss
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TWSG1 Polyclonal Antibody, HRP Conjugated - bs-11606R-HRP from Bioss
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Monoclonal Anti-TWSG1 antibody produced in mouse - WH0057045M1 from Sigma-Aldrich
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Monoclonal Anti-TWSG1 antibody produced in mouse - SAB1405201 from Sigma-Aldrich
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Anti-TWSG1 antibody produced in rabbit - HPA014898 from Sigma-Aldrich
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TWSG1-Antibody-monoclonal-M01 - AT4413a from Abgent, a WuXi AppTec company
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Mouse TSG Antibody - AF756 from R&D Systems
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