Gene Symbol | Il7r |
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Entrez Gene | 16197 |
Alt Symbol | CD127, IL-7Ralpha |
Species | Mouse |
Gene Type | protein-coding |
Description | interleukin 7 receptor |
Other Description | IL-7 receptor alpha chain|IL-7 receptor subunit alpha|IL-7R subunit alpha|IL-7R-alpha|IL-7RA|interleukin 7 receptor alpha chain|interleukin-7 receptor subunit alpha |
Swissprots | Q9R0C1 P16872 |
Accessions | EDL03312 P16872 AA183527 AF078906 AAF06717 AK040364 BAC30571 AK040740 BAC30689 AK041838 BAC31080 AK042264 BAC31208 AK154215 AK154516 BAE32645 AW986802 BC089571 AAH89571 BY776757 M29697 AAA39304 NM_008372 NP_032398 |
Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Spleen, thymus and fetal liver. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency, PI3K-Akt signaling pathway |
IL-7R CRISPR/Cas9 KO Plasmid (m) - sc-421118 from Santa Cruz Biotechnology
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IL-7R HDR Plasmid (m) - sc-421118-HDR from Santa Cruz Biotechnology
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IL-7R Double Nickase Plasmid (m) - sc-421118-NIC from Santa Cruz Biotechnology
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IL-7R Double Nickase Plasmid (m2) - sc-421118-NIC-2 from Santa Cruz Biotechnology
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IL-7R CRISPR Activation Plasmid (m) - sc-421118-ACT from Santa Cruz Biotechnology
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IL-7R CRISPR Activation Plasmid (m2) - sc-421118-ACT-2 from Santa Cruz Biotechnology
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IL-7R Lentiviral Activation Particles (m) - sc-421118-LAC from Santa Cruz Biotechnology
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IL-7R Lentiviral Activation Particles (m2) - sc-421118-LAC-2 from Santa Cruz Biotechnology
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IL-7R siRNA (m) - sc-35665 from Santa Cruz Biotechnology
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IL-7R shRNA Plasmid (m) - sc-35665-SH from Santa Cruz Biotechnology
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IL-7R shRNA (m) Lentiviral Particles - sc-35665-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33809 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33809 from Sigma-Aldrich
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IL7R siRNA (Mouse) - CRM2071 from Cohesion Biosciences
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IL7R - MBS8201751 from MyBioSource
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shRNA set against Mouse IL7R (NM_008372.4) - SHH319101 from Creative biogene
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shRNA set against Mouse Il7r(NM_008372.4) - SHL176192 from Creative biogene
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IL7R shRNA Plasmid (Mouse) - CHM2071 from Cohesion Biosciences
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IL7R miRNA 3'UTR clone - MiUTR1M-06019 from Creative biogene
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