Ptprc

Gene Symbol	Ptprc
Entrez Gene	19264
Alt Symbol	B220, CD45R, Cd45, L-CA, Ly-5, Lyt-4, T200, loc
Species	Mouse
Gene Type	protein-coding
Description	protein tyrosine phosphatase, receptor type, C
Other Description	leukocyte common antigen|lymphocyte antigen 5|lymphocyte common antigen|receptor-type tyrosine-protein phosphatase C
Swissprots	P06800 E9QLT5 Q61812 Q61813 Q61814 Q61815 Q78EF1
Accessions	AAA39418 AAA39460 AAA39462 AAB46374 CAJ01231 EDL39541 EDL39542 P06800 AK054056 BAC35638 AK079399 AK088215 AK088875 AK154893 BAE32907 AK169451 AK171802 AK172193 BC028512 AAH28512 BC084684 AAH84684 BC131655 BC167212 AAI67212 BM239381 BX517622 CA575153 CA577897 CK392851 EF101553 ABK96802 L36091 M11934 AAA39461 M14342 AAA39458 M14343 M15174 AAA40161 M17320 AAA60449 M92933 AAA39459 XM_006529257 XP_006529320 XM_006529258 XP_006529321 XM_006529259 XP_006529322 XM_006529260 XP_006529323 XM_006529261 XP_006529324 XM_006529262 XP_006529325 NM_001111316 NP_001104786 NM_001268286 NP_001255215 NM_011210 NP_035340
Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity. {ECO:0000250, ECO:0000269|PubMed:10415030}.
Subcellular Location	Membrane; Single-pass type I membrane protein. Membrane raft {ECO:0000250}. Note=Colocalized with DPP4 in membrane rafts. {ECO:0000250}.
Top Pathways	T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Fc gamma R-mediated phagocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cluster of differentiation 45 (CD45), Mouse, ELISA Kit - CSB-E14098m from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Cluster of differentiation 45 (CD45), Mouse, ELISA Kit - E03C2410 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Leukocyte Common Antigen, LCA/CD45, Mouse, ELISA Kit - YHB0855Mo from ARP American Research Products Category ELISA Kit

Receptor-type tyrosine-protein phosphatase C, Ptprc, Mouse, ELISA Kit - E1030m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

leukocyte common antigen, LCA/CD45, ELISA Kit - MBS9304930 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

protein tyrosine phosphatase, receptor type, C, ELISA Kit - MBS700735 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MagniSort™ Mouse CD45 Positive Selection Kit - 8802-6865 from eBioscience Prices $609.00 Sizes 200 tests

MagniSort™ Mouse CD45 Depletion Kit - 8804-6864 from eBioscience Prices $609.00 Sizes 200 tests

Mouse cluster of differentiation 45(CD45) ELISA Kit - CSB-E14098m from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

Mouse CD45 ELISA Kit - E048690 from Biobool Category ELISA Kit

Mouse Ptprc ELISA Kit - E065370 from Biobool Category ELISA Kit

Mouse Cluster of differentiation 45 (CD45) ELISA Kit - AE25078MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.039 ng/mL Range 0.156-10 ng/mL

Receptor-type tyrosine-protein phosphatase C, ELISA Kit - MBS2885850 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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