| Gene Symbol | Bcat2 |
|---|---|
| Entrez Gene | 64203 |
| Alt Symbol | BCT2, Bcatm, mBcat |
| Species | Rat |
| Gene Type | protein-coding |
| Description | branched chain amino acid transaminase 2, mitochondrial |
| Other Description | BCAT(m)|branched chain aminotransferase 2, mitochondrial|branched-chain-amino-acid aminotransferase, mitochondrial|heart branched chain aminotransferase precursor encoding mitochondrial protein |
| Swissprots | O35854 |
| Accessions | EDM07328 EDM07329 O35854 BC061790 AAH61790 U68417 AAB67673 XM_006229149 XP_006229211 XM_008759413 XP_008757635 NM_022400 NP_071795 |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. {ECO:0000269|PubMed:8428987}. |
| Subcellular Location | Mitochondrion. |
| Tissue Specificity | Expressed in all tissues. |
| Top Pathways | Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Valine, leucine and isoleucine degradation, Pantothenate and CoA biosynthesis |
CompoZr® Knockout ZFN Kit - CKOZFN51116 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND51116 from Sigma-Aldrich
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BCAT2 siRNA (Rat) - CRR1841 from Cohesion Biosciences
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BCAT2 - MBS8206834 from MyBioSource
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shRNA set against Rat BCAT2 (NM_022400.1) - SHH245770 from Creative biogene
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shRNA set against Rat Bcat2(NM_022400.1) - SHG096839 from Creative biogene
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Rat BCAT2 siRNA - orb296690 from Biorbyt
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BCAT2 shRNA Plasmid (Rat) - CHR1841 from Cohesion Biosciences
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BCAT2 miRNA 3'UTR clone - MiUTR1R-00529 from Creative biogene
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