WDR5

Gene Symbol WDR5
Entrez Gene 11091
Alt Symbol BIG-3, CFAP89, SWD3
Species Human
Gene Type protein-coding
Description WD repeat domain 5
Other Description BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD repeat-containing protein 5|WD-repeat protein 5|cilia and flagella associated protein 89
Swissprots P61964
Accessions CAD34861 EAW88117 EAW88118 EAW88119 EAW88120 P61964 AA490313 AJ011376 CAB66159 AK000552 BAA91248 AK024484 BAB15774 AK025810 BC001635 AAH01635 BC015594 BC029769 BG773451 HQ448239 ADQ32719 XM_005272163 XP_005272220 NM_017588 NP_060058 NM_052821 NP_438172
Function Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. {ECO:0000269|PubMed:16600877, ECO:0000269|PubMed:16829960, ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20018852}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17355966, ECO:0000269|PubMed:20018852}.

Rabbit anti-WDR5 Antibody, Affinity Purified - PLA0256 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

WD repeat domain 5, ELISA Kit - MBS9341940 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

WD repeat-containing protein 5, ELISA Kit - MBS283495 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human WDR5 ELISA Kit - E040537 from Biobool

Category ELISA Kit

anti-WDR5 antibody - ARG55015 from Arigo Biolaboratories

Category ELISA Kit
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