Gene Symbol | Srprb |
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Entrez Gene | 20818 |
Alt Symbol | AA409543 |
Species | Mouse |
Gene Type | protein-coding |
Description | signal recognition particle receptor, B subunit |
Other Description | SR-beta|signal recognition particle receptor subunit beta |
Swissprots | P47758 Q544X9 Q9D872 |
Accessions | EDL21065 P47758 AK004854 BAB23618 AK007859 BAB25311 AK008383 BAB25638 AK015469 BAB29860 AK030437 BAC26963 AK075583 BAC35836 AK160600 AK167039 BAE39207 AK179126 AK179649 AK181904 AK182239 AK186925 AK202233 AK204241 AK208005 AK216962 AK219957 BC003798 AAH03798 U17343 AAA69976 NM_009275 NP_033301 |
Function | Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
Top Pathways | Protein export |
SR-β siRNA (m) - sc-153813 from Santa Cruz Biotechnology
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SR-β shRNA Plasmid (m) - sc-153813-SH from Santa Cruz Biotechnology
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SR-β shRNA (m) Lentiviral Particles - sc-153813-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU035271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42051 from Sigma-Aldrich
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SRPRB siRNA (Mouse) - CRM3920 from Cohesion Biosciences
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SRPRB - MBS8228879 from MyBioSource
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shRNA set against Mouse SRPRB (NM_009275.4) - SHH418040 from Creative biogene
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shRNA set against Mouse Srprb(NM_009275.4) - SHL035256 from Creative biogene
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SRPRB shRNA Plasmid (Mouse) - CHM3920 from Cohesion Biosciences
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SRPRB miRNA 3'UTR clone - MiUTR1M-11240 from Creative biogene
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