| Gene Symbol | PLA2G4C |
|---|---|
| Entrez Gene | 8605 |
| Alt Symbol | CPLA2-gamma |
| Species | Human |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| Other Description | cytosolic phospholipase A2 gamma|phospholipase A2 group IVC |
| Swissprots | O75457 B2RB71 Q6IBI8 Q9UP65 B4DI40 Q9UG68 |
| Accessions | AAR25453 BAC87744 BAC87745 BAC87746 EAW52311 EAW52312 EAW52313 EAW52314 EAW52315 Q9UP65 AF058921 AAC32823 AF065214 AAC78835 AK022440 AK124241 AK126152 AK295400 BAG58352 AK314524 BAG37118 AL050193 CAB43312 BC017956 AAH17956 BC063416 AAH63416 CR456816 CAG33097 XM_011527431 XP_011525733 XM_011527432 XP_011525734 XM_011527433 XP_011525735 XM_011527434 XP_011525736 NM_001159322 NP_001152794 NM_001159323 NP_001152795 NM_003706 NP_003697 |
| Function | Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. {ECO:0000269|PubMed:10085124}. |
| Subcellular Location | Membrane {ECO:0000269|PubMed:10085124}; Lipid-anchor {ECO:0000269|PubMed:10085124}. |
| Tissue Specificity | Highly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:9705332}. |
| Top Pathways | Long-term depression, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels |