| Gene Symbol |
PLA2G4C
|
| Entrez Gene |
8605
|
| Alt Symbol |
CPLA2-gamma
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IVC (cytosolic, calcium-independent)
|
| Other Description |
cytosolic phospholipase A2 gamma|phospholipase A2 group IVC
|
| Swissprots |
O75457 B2RB71 Q6IBI8 Q9UP65 B4DI40 Q9UG68
|
| Accessions |
AAR25453 BAC87744 BAC87745 BAC87746 EAW52311 EAW52312 EAW52313 EAW52314 EAW52315 Q9UP65 AF058921 AAC32823 AF065214 AAC78835 AK022440 AK124241 AK126152 AK295400 BAG58352 AK314524 BAG37118 AL050193 CAB43312 BC017956 AAH17956 BC063416 AAH63416 CR456816 CAG33097 XM_011527431 XP_011525733 XM_011527432 XP_011525734 XM_011527433 XP_011525735 XM_011527434 XP_011525736 NM_001159322 NP_001152794 NM_001159323 NP_001152795 NM_003706 NP_003697
|
| Function |
Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. {ECO:0000269|PubMed:10085124}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:10085124}; Lipid-anchor {ECO:0000269|PubMed:10085124}.
|
| Tissue Specificity |
Highly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:10085124, ECO:0000269|PubMed:9705332}.
|
| Top Pathways |
Long-term depression, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels
|
![Western Blot: PLA2G4C Overexpression Lysate (Adult Normal) [NBL1-14475] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PLA2G4C.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/10921_PLA2G4C%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-14475-img0002.jpg)