Gene Symbol | Gpi1 |
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Entrez Gene | 14751 |
Alt Symbol | Amf, Gpi, Gpi-1, Gpi-1r, Gpi-1s, Gpi-1t, Gpi1-r, Gpi1-s, Gpi1-t, Gpi1s, MF, NK, NK/GPI, Nlk, Org, Pgi, Phi |
Species | Mouse |
Gene Type | protein-coding |
Description | glucose phosphate isomerase 1 |
Other Description | autocrine motility factor|glucose phosphate isomerase 1 complex|glucose phosphate isomerase 1, regulatory|glucose phosphate isomerase 1, structural|glucose phosphate isomerase 1, temporal|glucose-6-phosphate isomerase|maturation factor|neuroleukin|phosphoglucose isomerase|phosphohexose isomerase |
Swissprots | Q3UZJ1 Q8C675 P06745 Q3TW50 Q5RJI3 O89062 Q9JM07 Q3TEE7 Q3UUX1 Q3UY84 |
Accessions | P06745 AF108354 AAF28799 AK031081 AK076424 BAC36335 AK133827 BAE21866 AK134890 BAE22329 AK137805 BAE23502 AK147124 BAE27695 AK150341 BAE29481 AK152508 AK159838 BAE35416 AK164566 AK169681 BAE41301 AK171956 AK178353 AK194043 AK196108 AK197318 AK199629 AK204031 AK217121 BC086640 AAH86640 BC088995 AAH88995 BC157972 AAI57973 BC172124 AAI72124 BY287889 BY350616 L09104 AAA65641 M14220 AAA39825 U89408 AAC36515 NM_008155 NP_032181 |
Function | Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. |
Subcellular Location | Cytoplasm. Secreted. |
Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Amino sugar and nucleotide sugar metabolism, Carbon metabolism, Starch and sucrose metabolism |
GPI CRISPR/Cas9 KO Plasmid (m) - sc-420647 from Santa Cruz Biotechnology
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GPI HDR Plasmid (m) - sc-420647-HDR from Santa Cruz Biotechnology
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GPI Double Nickase Plasmid (m) - sc-420647-NIC from Santa Cruz Biotechnology
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GPI Double Nickase Plasmid (m2) - sc-420647-NIC-2 from Santa Cruz Biotechnology
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GPI CRISPR Activation Plasmid (m) - sc-420647-ACT from Santa Cruz Biotechnology
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GPI CRISPR Activation Plasmid (m2) - sc-420647-ACT-2 from Santa Cruz Biotechnology
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GPI Lentiviral Activation Particles (m) - sc-420647-LAC from Santa Cruz Biotechnology
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GPI Lentiviral Activation Particles (m2) - sc-420647-LAC-2 from Santa Cruz Biotechnology
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GPI siRNA (m) - sc-44813 from Santa Cruz Biotechnology
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GPI shRNA Plasmid (m) - sc-44813-SH from Santa Cruz Biotechnology
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GPI shRNA (m) Lentiviral Particles - sc-44813-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU094371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN32679 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32679 from Sigma-Aldrich
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GPI siRNA (Mouse) - CRM1653 from Cohesion Biosciences
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GPI - MBS8217905 from MyBioSource
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shRNA set against Mouse Gpi1 (NM_008155.3) - SHH305910 from Creative biogene
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Mouse GPI siRNA - orb281129 from Biorbyt
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GPI shRNA Plasmid (Mouse) - CHM1653 from Cohesion Biosciences
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