REG4

Gene Symbol REG4
Entrez Gene 83998
Alt Symbol GISP, REG-IV, RELP
Species Human
Gene Type protein-coding
Description regenerating islet-derived family, member 4
Other Description REG-4|REG-like protein|gastrointestinal secretory protein|reg IV|regenerating gene type IV|regenerating islet-derived protein 4|regenerating islet-derived protein IV
Swissprots Q8NER7 Q8NER6 Q9BYZ8
Accessions CAK22302 EAW56711 EAW56712 EAW56713 EAW56714 Q9BYZ8 AF254415 AAK48435 AF345934 AAK59869 AK057107 AY007243 AAG02562 AY126670 AAM95598 AY126671 AAM95599 AY126672 AAM95600 BC017089 AAH17089 BF242936 DQ891767 ABM82693 DQ894951 ABM85877 NM_001159352 NP_001152824 NM_001159353 NP_001152825 NM_032044 NP_114433
Function Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. {ECO:0000269|PubMed:12819006, ECO:0000269|PubMed:20692269}.
Subcellular Location Secreted {ECO:0000269|PubMed:12819006}.
Tissue Specificity Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. {ECO:0000269|PubMed:11311942, ECO:0000269|PubMed:12455032, ECO:0000269|PubMed:12819006}.

Reg IV CRISPR/Cas9 KO Plasmid (h) - sc-404117 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV HDR Plasmid (h) - sc-404117-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV Double Nickase Plasmid (h) - sc-404117-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV Double Nickase Plasmid (h2) - sc-404117-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV CRISPR Activation Plasmid (h) - sc-404117-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV CRISPR Activation Plasmid (h2) - sc-404117-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV Lentiviral Activation Particles (h) - sc-404117-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV Lentiviral Activation Particles (h2) - sc-404117-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Reg IV siRNA (h) - sc-61448 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Reg IV shRNA Plasmid (h) - sc-61448-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Reg IV shRNA (h) Lentiviral Particles - sc-61448-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU082771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18134 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18134 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13006 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13006

REG4 siRNA (Human) - CRJ3263 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

REG4 - MBS8208842 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human REG4 (NM_032044.3) - SHH391776 from Creative biogene

Category siRNA
Species Reactivities Human

Human REG4 siRNA - orb273764 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

REG4 shRNA Plasmid (Human) - CHJ3263 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

REG4 miRNA 3'UTR clone - MiUTR4H-TG07438 from Creative biogene

Species Reactivities Human
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