Gene Symbol | Aldoa |
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Entrez Gene | 11674 |
Alt Symbol | Aldo-1, Aldo1 |
Species | Mouse |
Gene Type | protein-coding |
Description | aldolase A, fructose-bisphosphate |
Other Description | aldolase 1, A isoform|fructose-bisphosphate aldolase A|muscle-type aldolase |
Swissprots | P05064 |
Accessions | AAA37210 EDL17440 EDL17442 EDL17445 P05064 AK002561 AK011238 AK145639 BAE26557 AK154295 BAE32496 AK162290 AK202323 BC043026 AAH43026 BC050896 AAH50896 BC066218 AAH66218 BC066801 AAH66801 BC089495 AAH89495 BY146617 BY785997 CF617557 CN694938 EF437341 EF662059 ABR58859 EF662060 ABR58860 HG980219 W64776 X03797 CAA27423 Y00516 CAA68571 XM_006507209 XP_006507272 XM_006507210 XP_006507273 XM_006507211 XP_006507274 XR_869640 XR_869641 XR_869642 NM_001177307 NP_001170778 NM_001177308 NP_001170779 NM_007438 NP_031464 |
Function | Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+). {ECO:0000250}. |
Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Biosynthesis of amino acids, Carbon metabolism, Fructose and mannose metabolism |
Aldolase A CRISPR/Cas9 KO Plasmid (m) - sc-419082 from Santa Cruz Biotechnology
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Aldolase A HDR Plasmid (m) - sc-419082-HDR from Santa Cruz Biotechnology
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Aldolase A Double Nickase Plasmid (m) - sc-419082-NIC from Santa Cruz Biotechnology
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Aldolase A Double Nickase Plasmid (m2) - sc-419082-NIC-2 from Santa Cruz Biotechnology
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Aldolase A CRISPR Activation Plasmid (m) - sc-419082-ACT from Santa Cruz Biotechnology
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Aldolase A CRISPR Activation Plasmid (m2) - sc-419082-ACT-2 from Santa Cruz Biotechnology
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Aldolase A Lentiviral Activation Particles (m) - sc-419082-LAC from Santa Cruz Biotechnology
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Aldolase A Lentiviral Activation Particles (m2) - sc-419082-LAC-2 from Santa Cruz Biotechnology
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Aldolase A siRNA (m) - sc-29665 from Santa Cruz Biotechnology
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Aldolase A shRNA Plasmid (m) - sc-29665-SH from Santa Cruz Biotechnology
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Aldolase A shRNA (m) Lentiviral Particles - sc-29665-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU092241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26561 from Sigma-Aldrich
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ALDOA siRNA (Mouse) - CRM0140 from Cohesion Biosciences
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ALDOA - MBS8231317 from MyBioSource
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shRNA set against Mouse ALDOA (NM_007438.4) - SHH235002 from Creative biogene
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Aldolase A CRISPR/Cas9 KO Plasmid (m2) - sc-419082-KO-2 from Santa Cruz Biotechnology
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Aldolase A HDR Plasmid (m2) - sc-419082-HDR-2 from Santa Cruz Biotechnology
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Mouse ALDOA siRNA - orb279616 from Biorbyt
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ALDOA shRNA Plasmid (Mouse) - CHM0140 from Cohesion Biosciences
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