Gene Symbol | F10 |
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Entrez Gene | 2159 |
Alt Symbol | FX, FXA |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor X |
Other Description | Stuart-Prower factor|factor Xa|prothrombinase |
Swissprots | Q14340 P00742 |
Accessions | AAA52636 AAA52764 AAM19347 ACA06104 BAA21634 CAL24230 EAX09184 EAX09185 P00742 AK310772 AK310775 AK313798 BAG36534 BC040125 BC046125 AAH46125 CB158437 K01886 AAA52486 K03194 AAA52490 M22613 AAA51984 M57285 AAA52421 XM_005268298 XP_005268355 NM_000504 NP_000495 |
Function | Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
Subcellular Location | Secreted. |
Tissue Specificity | Plasma; synthesized in the liver. {ECO:0000269|PubMed:6587384}. |
Top Pathways | Complement and coagulation cascades |
Factor X CRISPR/Cas9 KO Plasmid (h) - sc-404175 from Santa Cruz Biotechnology
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Factor X HDR Plasmid (h) - sc-404175-HDR from Santa Cruz Biotechnology
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Factor X Double Nickase Plasmid (h) - sc-404175-NIC from Santa Cruz Biotechnology
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Factor X Double Nickase Plasmid (h2) - sc-404175-NIC-2 from Santa Cruz Biotechnology
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Factor X CRISPR Activation Plasmid (h) - sc-404175-ACT from Santa Cruz Biotechnology
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Factor X CRISPR Activation Plasmid (h2) - sc-404175-ACT-2 from Santa Cruz Biotechnology
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Factor X Lentiviral Activation Particles (h) - sc-404175-LAC from Santa Cruz Biotechnology
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Factor X Lentiviral Activation Particles (h2) - sc-404175-LAC-2 from Santa Cruz Biotechnology
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Factor X siRNA (h) - sc-40405 from Santa Cruz Biotechnology
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Factor X shRNA Plasmid (h) - sc-40405-SH from Santa Cruz Biotechnology
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Factor X shRNA (h) Lentiviral Particles - sc-40405-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1727 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1727 from Sigma-Aldrich
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F10 siRNA (Human) - CRH1501 from Cohesion Biosciences
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F10 - MBS8227919 from MyBioSource
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shRNA set against Human F10 (NM_000504.3) - SHH288361 from Creative biogene
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shRNA set against Human F10(NM_000504.3) - SHH043103 from Creative biogene
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F10 shRNA Plasmid (Human) - CHH1501 from Cohesion Biosciences
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F10 miRNA 3'UTR clone - MiUTR1H-03358 from Creative biogene
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