COL2A1

Gene Symbol COL2A1
Entrez Gene 1280
Alt Symbol ANFH, AOM, COL11A3, SEDC, STL1
Species Human
Gene Type protein-coding
Description collagen, type II, alpha 1
Other Description alpha-1 type II collagen|arthroophthalmopathy, progressive (Stickler syndrome)|cartilage collagen|chondrocalcin|collagen II, alpha-1 polypeptide|collagen alpha-1(II) chain
Swissprots Q14044 Q6LBY3 Q14045 Q96IT5 Q9UE43 A6NGA0 Q2V4X7 Q14046 P02458 Q14009 Q9UE40 Q9UE38 Q6LBY1 Q14056 Q1JQ82 Q6LBY2 Q9UE41 Q9UE39 Q12985 Q14058 Q99227 Q9UE42 Q14047 Q16672
Accessions AAA51997 AAA52037 AAA52039 AAA52051 AAA58428 AAA73873 AAB60370 AAC41772 AAD14239 AAD15286 AAD15287 CAA25092 CAA26223 CAA26224 CAA26225 CAA26226 CAA26227 CAA27041 CAA34278 CAA34279 CAA34280 CAA34281 CAA34282 CAA34283 CAA34284 CAA40330 CAI61687 CDM55396 CDM55577 EAW57966 EAW57967 EAW57968 EAW57969 EAW57970 P02458 AL834148 CAI46208 BC007252 AAH07252 BC116449 AAI16450 BT007205 AAP35869 HG504715 HG504716 LN608441 M63281 AAA52038 X06268 CAA29604 X13783 CAA32030 X16468 CAA34488 X16711 CAA34683 XM_006719242 XP_006719305 XM_011537928 XP_011536230 XM_011537929 XP_011536231 XM_011537930 XP_011536232 XM_011537931 XP_011536233 XM_011537932 XP_011536234 XM_011537933 XP_011536235 XM_011537934 XP_011536236 XM_011537935 XP_011536237 NM_001844 NP_001835 NM_033150 NP_149162
Function Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Tissue Specificity Isoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte. {ECO:0000269|PubMed:2355003}.
Top Pathways Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway

Collagen II peptide - ab105995 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg

Cow Collagen II full length protein - ab7527 from Abcam

Category Protein
Prices $235.00
Sizes 500 µg
Source Native
Species Bovine

Cow Collagen II full length protein - ab134539 from Abcam

Category Protein
Source Native
Species Bovine
SDS PAGE analysis of Collagen proteins Lane 1: Rat tail Collagen I Lane 2: Molecular weight marker Lane 3: Bovine naval septum Collagen II (ab134539) Lane 4: Human naval septum Collagen II

Cow Collagen II full length protein - ab134530 from Abcam

Category Protein
Source Native
Species Bovine

Human Collagen II full length protein - ab7534 from Abcam

Category Protein
Source Native
Species Human

Human Collagen II full length protein - ab134522 from Abcam

Category Protein
Source Native
Species Human
SDS-PAGE analysis of ab134522 Lane 1: Molecular weight marker Lane 2: ab134522

Human Collagen II full length protein - ab134534 from Abcam

Category Protein
Source Native
Species Human
SDS PAGE analysis of Collagen proteins Lane 1: Rat tail Collagen I Lane 2: Molecular weight marker Lane 3: Bovine naval septum Collagen II Lane 4: Human naval septum Collagen II (ab134534)

Human procollagen type IIA full length protein - ab158154 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158154 on a 12.5% SDS-PAGE stained with Coomassie Blue.

COL2A1 / Collagen II Alpha 1 Antibody Blocking Peptide - LS-E3054 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Collagen II Protein - H00001280-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Collagen II Protein - NBP1-97301 from Novus Biologicals

Category Protein
Species Human

Collagen II Peptide - P0384 from Novus Biologicals

Category Peptide
Species Human

Collagen II Protein - P4917 from Novus Biologicals

Category Protein
Prices $1,559.00
Sizes 1 mg
Species Human

Collagen II Human Expressed Protein - P4916 from Novus Biologicals

Category Protein
Prices $1,559.00
Sizes 1 mg
Species Human

COL2A1-Antibody-C-term-Blocking-Peptide - BP1418b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Pro-Collagen II, CF - 7589-CL-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Gln26-Arg266 & Gly957-Leu1487, with an N-terminal 5-His tag

Collagen Type II protein - 30R-AC015 from Fitzgerald

Category Protein
Prices $795.00
Sizes 100 µg

Collagen type II alpha 1 chain (Adult Knee Cartilage) - RA003 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 100 µg
Source Cartilage
Species Human

Collagen type II alpha 1 chain - H00001280-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Collagen type II alpha 1 chain - H00001280-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Collagen type II alpha 1 chain - P4916 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 1 mg
Species Human

Collagen type II alpha 1 chain - P4917 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 1 mg
Species Human

Collagen Type II Alpha 1 (COL2a1), Human - 20-8711 from ARP American Research Products

Category Protein
Prices $511.00
Sizes 50 µg
Source E.coli
Species Human

COL2A1 Recombinant Protein - 96-195 from ProSci

Category Protein
Prices $425.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh COL2A1 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

COL2A1 fusion protein - Ag8416 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human
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