MARCKS

Gene Symbol MARCKS
Entrez Gene 4082
Alt Symbol 80K-L, MACS, PKCSL, PRKCSL
Species Human
Gene Type protein-coding
Description myristoylated alanine-rich protein kinase C substrate
Other Description myristoylated alanine-rich C-kinase substrate|myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)|phosphomyristin|protein kinase C substrate, 80 kDa protein, light chain
Swissprots Q2LA83 E1P560 Q5TDB7 P29966
Accessions AAA59554 ABC67467 CAI19942 CAJ01280 EAW48258 EAW48259 P29966 AI142997 AK027274 AK074526 AW163148 BC013004 AAH13004 BC028284 AAH28284 BC039492 BC068059 AAH68059 BC089040 AAH89040 BU678392 CN345330 D10522 BAA01392 EU832331 ACE87588 EU832416 ACE86901 HY144763 M68956 AAA59555 NM_002356 NP_002347
Function MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000305}. Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
Top Pathways Fc gamma R-mediated phagocytosis, MicroRNAs in cancer

Phospho-MARCKS (Ser167/170) (D13E4) XP ® Rabbit mAb - 8722 from Cell Signaling Technology

Prices $119.00, $318.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D13E4
Western blot analysis of extracts from serum-starved SH-SY5Y and SK-N-MC cells, untreated (-) or treated with TPA #4174 (200 nM, 15 min; +), using Phospho-MARCKS (Ser167/170) (D13E4) XP ® Rabbit mAb (upper) and MARCKS (D88D11) XP ® Rabbit mAb #5607 (lower).

Phospho-MARCKS (Ser159/163) (D13D2) Rabbit mAb - 11992 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D13D2
Western blot analysis of extracts from HeLa, NIH/3T3, and C6 cells, serum starved overnight and either DMSO-treated or treated with TPA #4174 (200 nM, 15 min), using Phospho-MARCKS (Ser159/163) (D13D2) Rabbit mAb.

Phospho-MARCKS (Ser152/156) Antibody - 2741 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from NIH/3T3 and C6 cells starved for 16 hours and treated with TPA (0.2 µM) for 30 minutes.

MARCKS (D88D11) XP ® Rabbit mAb - 5607 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D88D11
Western blot analysis of cell extracts from various cell lines using MARCKS (D88D11) XP ® Rabbit mAb.

MARCKS (C-19) - sc-6453 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MARCKS (C-19): sc-6453 Immunofluorescence staining of methanol-fixed SK-N-SH cells showing cytoplasmic staining.

MARCKS (M-20) - sc-6455 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of MARCKS expression in SK-N-SH whole cell lysates (A-C). Antibodies tested include MARCKS (C-19): sc-6453 (A), MARCKS (N-19): sc-6454 (B) and MARCKS (M-20): sc-6455 (C).

MARCKS (N-19) - sc-6454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MARCKS (N-19): sc-6454. Immunofluorescence staining of methanol-fixed SK-N-SH cells showing cytoplasmic staining.

MARCKS (JK-8) - sc-100777 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MARCKS (JK-8): sc-100777. Western blot analysis of MARCKS expression in RAW 264.7 whole cell lysate.

p-MARCKS (Ser 159/163) - sc-12971 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-MARCKS (Ser 159/163): sc-12971. Western blot analysis of MARCKS phosphorylation in non-transfected 293T: sc-117752 (A), mouse MARCKS transfected 293T: sc-121515 (B) and SK-N-SH (C) whole cell lysates.

p-MARCKS (Ser 159) - sc-101730 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of phosphorylated MARCKS expression in starved NIH/3T3 whole cell lysates (A,B). Blots were probed with p-MARCKS (Ser 159): 101730 preincubated with its cognate phosphorylated peptide (A) and p-MARCKS (Ser 159): 101730 (B).

p-MARCKS (Ser 170) - sc-293104 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-MARCKS (Ser 170): sc-293104. Western blot analysis of MARCKS phosphorylation expression in untreated (A) and EGF treated (B) MCF7 whole cell lysates.

Anti-MARCKS (phospho S152 + S153) antibody - ab13811 from Abcam

Prices $359.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-MARCKS (phospho S152 + S156) antibody - ab32590 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MARCKS (phospho S152 + S156) antibody (ab32590) at 1/1000 dilutionLane 1 : Rat brain lysateLane 2 : Rat brain lysate with Ser152/156 phosphopeptide used as antigenLysates/proteins at 10 µg per lane.

Anti-MARCKS (phospho S158) antibody - ab138684 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MARCKS (phospho S158) antibody (ab138684) at 1/500 dilution + K562 cell extracts, treated with EGF (200ng/ml, 30 mins) at 30 µg

Anti-MARCKS (phospho S158) antibody [EP2113Y] - ab81295 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP2113Y
All lanes : Anti-MARCKS (phospho S158) antibody [EP2113Y] (ab81295) at 1/2000 dilution (purified)Lane 1 : Rat brainLane 2 : Mouse brainLysates/proteins at 10 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-MARCKS (phospho S162) antibody - ab194804 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MARCKS (phospho S162) antibody (ab194804) at 1/500 dilutionLane 1 : Untreated 293 cell extractLane 2 : PMA-treated 293 cell extract

Anti-MARCKS (phospho S162) antibody - ab119321 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab119321, at 1/100, staining MARCKS in methanol-fixed HeLa cells by immunofluorescence.

Anti-MARCKS (phospho S162) antibody - ab51070 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Human brain tissue labelled with ab51070 at 1/50 dilution.

Anti-MARCKS antibody - ab51100 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab51100 at 1/100 dilution staining MARCKS in paraffin embedded human brain sections by Immunohistochemistry, in the absence and presence of the immunizing (blocking) peptide.

Anti-MARCKS antibody - ab55451 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-MARCKS antibody - ab78885 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MARCKS antibody (ab78885) at 1/500 dilutionLane 1 : Extracts from Mouse brain cellsLane 2 : Extracts from Mouse brain cells with immunizing peptide at 5 µgLysates/proteins at 20 µg per lane.

Anti-MARCKS antibody - ab115337 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115337 at 10ug/ml staining MARCKS in Formalin-fixed, Paraffin-embedded Human brain (cortex) tissue by immunohistochemistry , followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MARCKS antibody [2C2] - ab117547 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2C2
ab117547, at 2.5 µg/ml, staining MARCKS in Formalin-fixed, Paraffin-embedded Human Tonsil tissue by Immunohistochemistry.

Anti-MARCKS antibody [EP1446Y] - ab52616 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1446Y
ICC/IF image of ab52616 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab52616 at 1/200 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-MARCKS Antibody (phospho-Ser170) - LS-C124053 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Search more