| Gene Symbol | MARCKS |
|---|---|
| Entrez Gene | 4082 |
| Alt Symbol | 80K-L, MACS, PKCSL, PRKCSL |
| Species | Human |
| Gene Type | protein-coding |
| Description | myristoylated alanine-rich protein kinase C substrate |
| Other Description | myristoylated alanine-rich C-kinase substrate|myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)|phosphomyristin|protein kinase C substrate, 80 kDa protein, light chain |
| Swissprots | Q2LA83 E1P560 Q5TDB7 P29966 |
| Accessions | AAA59554 ABC67467 CAI19942 CAJ01280 EAW48258 EAW48259 P29966 AI142997 AK027274 AK074526 AW163148 BC013004 AAH13004 BC028284 AAH28284 BC039492 BC068059 AAH68059 BC089040 AAH89040 BU678392 CN345330 D10522 BAA01392 EU832331 ACE87588 EU832416 ACE86901 HY144763 M68956 AAA59555 NM_002356 NP_002347 |
| Function | MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. |
| Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000305}. Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. |
| Top Pathways | Fc gamma R-mediated phagocytosis, MicroRNAs in cancer |