HLCS

Gene Symbol HLCS
Entrez Gene 3141
Alt Symbol HCS
Species Human
Gene Type protein-coding
Description holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Other Description biotin apo-protein ligase|biotin--[acetyl-CoA-carboxylase] ligase|biotin--[methylcrotonoyl-CoA-carboxylase] ligase|biotin--[methylmalonyl-CoA-carboxytransferase] ligase|biotin--protein ligase|holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
Swissprots B2RAH1 D3DSG6 P50747 Q99451
Accessions BAA89434 BAA95510 BAA95511 BAB68550 EAX09731 EAX09732 P50747 AJ001864 CAA05056 AK307940 AK314189 BAG36868 BC060787 AAH60787 BI094308 BQ775124 CB049233 D23672 BAA04902 D87328 BAA13332 DA334377 DB290499 H17102 X80160 XM_005260953 XP_005261010 XM_005260954 XP_005261011 XM_005260955 XP_005261012 XM_005260956 XP_005261013 XM_006723994 XP_006724057 XM_006723995 XP_006724058 XM_011529538 XP_011527840 XM_011529539 XP_011527841 XM_011529540 XP_011527842 XM_011529541 XP_011527843 XM_011529542 XP_011527844 NM_000411 NP_000402 NM_001242784 NP_001229713 NM_001242785 NP_001229714
Function Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.
Subcellular Location Cytoplasm. Mitochondrion.
Tissue Specificity Mostly expressed in muscle, placenta, in lesser extent in the brain, kidney, pancreas, liver and lung.
Top Pathways Biotin metabolism

HLCS protein (His-DHFR tag) - ab127602 from Abcam

Category Protein
Prices $364.00
Sizes 50 µg
Source E. coli
Species Human

Human HLCS full length protein - ab132809 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132809 stained with Coomassie Blue.

Recombinant Human HLCS Protein - H00003141-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human HLCS Protein - H00003141-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Biotin-protein ligase / HLCS - H00003141-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Biotin-protein ligase / HLCS - H00003141-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Biotin-protein ligase / HLCS - H00003141-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Biotin-protein ligase / HLCS - H00003141-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

HLCS fusion protein - ag5208 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

HLCS fusion protein - Ag5926 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human Biotin--protein ligase(HLCS) - CSB-YP010518HU CSB-EP010518HU CSB-BP010518HU CSB-MP010518HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Biotin-protein ligase / HLCS - TP309197 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Biotin-protein ligase / HLCS

HLCS Recombinant Protein Antigen - NBP1-81759PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

HLCS Peptide, Human - M34GP07105H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Biotin--protein ligase (HLCS), Recombinant Protein - MBS964962 from MyBioSource

Category Protein
Prices $1,535.00, $1,535.00, $1,765.00, $1,765.00, $2,635.00, $2,635.00, $3,080.00, $3,080.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more