NR5A2

Gene Symbol	NR5A2
Entrez Gene	2494
Alt Symbol	B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 5, group A, member 2
Other Description	CYP7A promoter-binding factor|alpha-1-fetoprotein transcription factor|b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus|fetoprotein-alpha 1 (AFP) transcription factor|hepatocytic transcription factor hB1F-3|liver nuclear receptor homolog-1 variant 2|liver receptor homolog 1|liver receptor homolog-1|nuclear receptor NR5A2|nuclear receptor subfamily 5 group A member 2
Swissprots	Q147U3 O95642 B4E2P3 O00482
Accessions	AAG17124 AAG17125 AAL37171 ACD87739 EAW91305 EAW91306 EAW91307 EAW91308 O00482 AB019246 BAA34092 AB307719 BAH02310 AF049102 AAD03248 AF112344 AF124247 AAD26565 AF124248 AAD26566 AF146343 AAD37378 AF228413 AK304344 BAG65188 AK304365 BAG65205 AK308446 AK316513 BAH14884 BC027893 BC118571 AAI18572 BC118652 AAI18653 CA776772 CB162803 HQ692857 ADZ17368 U80251 AAC78727 U93553 AAD03155 XM_005245062 XP_005245119 XM_011509380 XP_011507682 XM_011509381 XP_011507683 XM_011509382 XP_011507684 XM_011509383 XP_011507685 XM_011509384 XP_011507686 NM_001276464 NP_001263393 NM_003822 NP_003813 NM_205860 NP_995582
Function	Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR5A2 / LRH-1 ELISA Kit (Sandwich ELISA) - LS-F8998 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.112 ng/ml Range 0.313-20 ng/ml

Rat NR5A2 / LRH-1 ELISA Kit (Sandwich ELISA) - LS-F8999 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 0.313-20 ng/ml

Human LRH1 ELISA Kit - abx152231 from Abbexa Category ELISA Kit Sensitivity 0.112 ng/ml Range 0.313 ng/ml - 20 ng/ml

Liver Receptor Homolog 1 (LRH1), Human, ELISA Kit - SED965Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.112ng/mL Range 0.312-20ng/mL

Nuclear receptor subfamily 5 group A member 2, NR5A2, Human, ELISA Kit - E0297h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

nuclear receptor subfamily 5, group A, member 2, ELISA Kit - MBS9336445 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 7alpha (α)-Hydroxylase (CYP7A) - MBS9310106 from MyBioSource Category ELISA Kit

Liver Receptor Homolog 1, ELISA Kit - MBS104718 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS047924 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS084056 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS104628 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS050384 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS048340 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Liver Receptor Homolog 1, ELISA Kit - MBS087285 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Liver Receptor Homolog 1 (LRH1) - SED965Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.112ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Liver Receptor Homolog 1 (LRH1) - SED965Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Liver Receptor Homolog 1 (LRH1) - SED965Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.112ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human NR5A2 / LRH-1 ELISA Kit (Custom ELISA) - LS-F14228 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Rat NR5A2 / LRH-1 ELISA Kit (Custom ELISA) - LS-F14231 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Chicken NR5A2 / LRH-1 ELISA Kit (Custom ELISA) - LS-F14229 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Mouse NR5A2 / LRH-1 ELISA Kit (Custom ELISA) - LS-F14230 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human Liver Receptor Homolog 1 (LRH1) ELISA Kit - EKU05668 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.112 ng/mL Range 0.312-20 ng/mL

Liver Receptor Homolog 1 (LRH1), Human, ELISA Kit - DL-LRH1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human LRH1 ELISA Kit - abx573024 from Abbexa Category ELISA Kit Sensitivity 0.112 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human LRH1 ELISA Kit - E022908 from Biobool Category ELISA Kit Sensitivity Typically less than 0.112ng/mL.

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