| Gene Symbol |
ACSS1
|
| Entrez Gene |
84532
|
| Alt Symbol |
ACAS2L, ACECS1, AceCS2L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA synthetase short-chain family member 1
|
| Other Description |
acetate--CoA ligase 2|acetyl-coenzyme A synthetase 2-like, mitochondrial
|
| Swissprots |
Q96JX6 Q9NUB1 F5H6F4 B3KXL2 Q96JI1 F8W7Y1 Q9NU28 Q8IV99 Q8N234 B4DJZ3 D3DW48 Q5TF42
|
| Accessions |
EAX10106 EAX10107 EAX10108 EAX10109 EAX10110 EAX10111 Q9NUB1 AB058749 BAB47475 AK024396 AK024424 BAB15714 AK027817 BAB55390 AK090851 BAC03530 AK092295 BAC03853 AK094414 AK125058 BAC86035 AK125923 AK127566 BAG54524 AK296306 BAG59005 AK314440 AL832939 CAH56320 AL833041 CAH56303 AW024920 BC032076 BC039261 AAH39261 BC044588 AAH44588 BC055008 AAH55008 BC114612 AAI14613 BM150326 DC404033 XM_006723659 XP_006723722 XM_011529388 XP_011527690 XR_937170 NM_001252675 NP_001239604 NM_001252676 NP_001239605 NM_001252677 NP_001239606 NM_032501 NP_115890
|
| Function |
Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2). {ECO:0000250, ECO:0000269|PubMed:16788062}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000269|PubMed:16788062}.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Pyruvate metabolism, Carbon metabolism, Propanoate metabolism
|