| Gene Symbol | Grm7 |
|---|---|
| Entrez Gene | 81672 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | glutamate receptor, metabotropic 7 |
| Other Description | mGluR7|metabotropic glutamate receptor 7|metabotropic glutamate receptor mGluR7|metabotropic glutamate receptor subtype 7b |
| Swissprots | P35400 |
| Accessions | EDL91489 P35400 D16817 BAA04092 U06832 AAA20655 X96790 CAA65584 XM_008763199 XP_008761421 NM_031040 NP_112302 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8145723, ECO:0000269|PubMed:8288585}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely distributed throughout the brain. {ECO:0000269|PubMed:8145723, ECO:0000269|PubMed:8288585}. |
| Top Pathways | Glutamatergic synapse, Neuroactive ligand-receptor interaction |
CompoZr® Knockout ZFN Kit - CKOZFN54766 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND54766 from Sigma-Aldrich
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GRM7 siRNA (Rat) - CRR2296 from Cohesion Biosciences
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GRM7 - MBS8208448 from MyBioSource
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shRNA set against Rat GRM7 (NM_031040.1) - SHH308166 from Creative biogene
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shRNA set against Rat Grm7(NM_031040.1) - SHH105795 from Creative biogene
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Rat GRM7 siRNA - orb297145 from Biorbyt
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GRM7 shRNA Plasmid (Rat) - CHR2296 from Cohesion Biosciences
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GRM7 miRNA 3'UTR clone - MiUTR1R-02304 from Creative biogene
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