| Gene Symbol |
CHRNA5
|
| Entrez Gene |
1138
|
| Alt Symbol |
LNCR2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 5 (neuronal)
|
| Other Description |
Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5|acetylcholine receptor, nicotinic, alpha 5 (neuronal)|neuronal acetylcholine receptor subunit alpha-5|neuronal nicotinic acetylcholine receptor, alpha5 subunit
|
| Swissprots |
Q15824 Q99554 P30532
|
| Accessions |
CAC34820 EAW99160 EAW99161 EAW99162 P30532 AF385586 AJ584705 CAE48367 AJ584706 CAE48368 BC033639 AAH33639 BC050469 BM839817 BX332469 DQ893355 ABM84281 DQ896674 ABM87673 EU176798 ABW03599 M83712 AAA58357 U62434 AAB40112 Y08419 CAA69696 XM_005254142 XP_005254199 XM_011521174 XP_011519476 NM_000745 NP_000736 NM_001307945 NP_001294874
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|