CHIT1

Gene Symbol	CHIT1
Entrez Gene	1118
Alt Symbol	CHI3, CHIT, CHITD
Species	Human
Gene Type	protein-coding
Description	chitinase 1 (chitotriosidase)
Other Description	chitotriosidase-1|plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Swissprots	Q0VGG6 B3KNW6 Q9H3V8 Q0VGG5 Q13231 Q6ISC2 Q9UDJ8 J3KN09 Q3ZAR1
Accessions	EAW91469 EAW91470 EAW91471 Q13231 AI697695 AK055165 BAG51478 AK131093 BAC85143 AK225245 AK309341 AK314331 BC069614 AAH69614 BC103695 AAI03696 BC105680 AAI05681 BC105681 AAI05682 BC105682 AAI05683 BP297140 BP304256 BQ029424 BX096812 BX099272 U29615 AAC50246 U62662 AAG10644 XM_011509109 XP_011507411 XM_011509110 XP_011507412 XR_921732 NM_001256125 NP_001243054 NM_001270509 NP_001257438 NM_003465 NP_003456 NR_045784 NR_045785
Function	Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. {ECO:0000269|PubMed:7592832, ECO:0000269|PubMed:7836450}.
Subcellular Location	Secreted. Lysosome. Note=A small proportion is lysosomal.
Tissue Specificity	Detected in spleen. Secreted by cultured macrophages. {ECO:0000269|PubMed:7836450}.
Top Pathways	Amino sugar and nucleotide sugar metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CHIT1 full length protein - ab116981 from Abcam Category Protein Source Wheat germ Species Human

Human CHIT1 full length protein - ab151883 from Abcam Category Protein Source HEK 293 cells Species Human

Human CHIT1 protein fragment - ab116982 from Abcam Category Protein Source Wheat germ Species Human

CHIT1 / Chitotriosidase Antibody Blocking Peptide - LS-E27799 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Chitotriosidase/CHIT1 Protein - H00001118-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Chitotriosidase/CHIT1 Partial Recombinant Protein - H00001118-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Chitotriosidase/CHIT1, CF - 3559-GH-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala22-Asn466, with a C-terminal 10-His tag

Human CHI3 protein - orb83519 from Biorbyt Category Protein Prices $323.00, $527.00 Sizes 10 μg, 20 μg Source Human Species Human

Human CHIT1 protein - orb49295 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

CHIT1 Peptide - AC21-2610-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Chitinase 1 - H00001118-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Chitinase 1 - H00001118-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Chitinase 1 - H00001118-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Chitinase 1 - H00001118-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Chitotriosidase-1, CHIT1, Human, Recombinant - 19-C451 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source HEK293 Species Human

CHIT1 Peptide - 42-918P from ProSci Category Peptide Species Human

CHIT1 fusion protein - ag16039 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CHIT1 fusion protein - Ag17242 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CHIT1 Enzyme - BP001714-C451 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source HEK 293-derived. Species Human

Recombinant Human CHIT1, His tagged - CHIT1-658H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CHIT1 - CHIT1-27067TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CHIT1 - CHIT1-27068TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CHIT1, GST-tagged - CHIT1-11177H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CHIT1, His-tagged - CHIT1-535H from Creative Biomart Category Protein Source NSO Cells Species Human

CHIT1 - PN201299 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

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