GGCX

Gene Symbol GGCX
Entrez Gene 2677
Alt Symbol VKCFD1
Species Human
Gene Type protein-coding
Description gamma-glutamyl carboxylase
Other Description peptidyl-glutamate 4-carboxylase|vitamin K-dependent gamma-carboxylase
Swissprots Q6GU45 B4DMC5 P38435 E9PEE1 Q14415
Accessions AAB39832 AAF64245 AAY24340 ABV02114 EAW99509 EAW99510 P38435 AK054569 AK130139 AK222827 BAD96547 AK225663 AK297397 BAG59837 AK298982 BAG61076 AK310483 AK313126 BAG35946 BC004422 BC013979 AAH13979 BM974022 DC296316 DQ892948 ABM83874 DQ896196 ABM87195 EU847509 ACF70731 L17128 AAA91834 M81592 AAA58643 XM_005264259 XP_005264316 XM_011532764 XP_011531066 XM_011532765 XP_011531067 XR_939677 NM_000821 NP_000812 NM_001142269 NP_001135741
Function Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. {ECO:0000269|PubMed:17073445}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10910912}; Multi-pass membrane protein {ECO:0000269|PubMed:10910912}.
Top Pathways Ubiquinone and other terpenoid-quinone biosynthesis

GGCX (H-135) - sc-98671 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

GGCX (N-14) - sc-79252 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GGCX (N-14): sc-79252. Western blot analysis of GGCX expression in mouse liver tissue extract.

Anti-GGCX antibody - ab197982 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GGCX antibody (ab197982) at 1/400 dilutionLane 1 : MCF7 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLysates/proteins at 40 µg per lane.

Anti-GGCX antibody - ab107507 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GGCX antibody (ab107507) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-GGCX antibody - ab106924 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-GGCX antibody (ab106924) at 0.3 µg/ml (for 1 hour) + Human Muscle lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-GGCX antibody [EPR11632] - ab170921 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11632
Immunofluorescent staining of HeLa cells labeling GGCX with ab170921 at 1/100 (green). DAPI nuclear staining (blue).

Anti-GGCX Antibody (aa548-578, AP) - LS-C257706 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa548-578, FITC) - LS-C257709 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa548-578, APC) - LS-C257707 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa548-578, Biotin) - LS-C257708 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa548-578, PE) - LS-C257711 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa548-578, Azide-free, HRP) - LS-C257710 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa555-585) - LS-C321615 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX Antibody (aa533-630, Azide-free) - LS-C327438 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-GGCX Antibody (aa684-733) - LS-C102091 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GGCX antibody LS-C102091 Western blot of MCF7 cell lysate.

Anti-GGCX Antibody (aa548-578) - LS-C166455 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GGCX Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GGCX Antibody (aa746-757) IHC-plus™ - LS-B10319 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GGCX antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10319 concentration 5 ug/ml.

GGCX Antibody - NBP1-59394 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GGCX Antibody - NBP2-16651 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GGCX Antibody [NBP2-16651] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa C: HepG2 7. 5% SDS PAGE gel, diluted at 1:3000.

GGCX Antibody - NBP1-80624 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-80624] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

GGCX Antibody - NBP1-51964 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: GGCX Antibody [NBP1-51964] - Analysis of GGCX in Human Muscle lysate (35ug protein in RIPA buffer) using NBP1-51964 at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

GGCX Antibody - H00002677-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

GGCX Polyclonal Antibody - bs-7759R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GGCX (C-terminal) antibody produced in goat - SAB2501277 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GGCX (C-terminal): <B>Cat. No. SAB2501277</B>: (0.3 μg/mL) staining of Human Muscle lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-GGCX antibody produced in rabbit - SAB2100912 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GGCX: <B>Cat. No.SAB2100912</B>: GGCX in MCF7 cell lysate with GGCX antibody at 1.0 μg/mL.
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