ABHD6

Gene Symbol ABHD6
Entrez Gene 57406
Alt Symbol -
Species Human
Gene Type protein-coding
Description abhydrolase domain containing 6
Other Description 2-arachidonoylglycerol hydrolase|abhydrolase domain-containing protein 6|lipase protein|monoacylglycerol lipase ABHD6
Swissprots Q6ZMF7 B2R7Y9 Q9BV23
Accessions CAC39533 EAW65360 EAW65361 EAW65362 EAW65363 EAW65364 EAW65365 Q9BV23 AF225418 AAG09720 AK092841 AK122983 BAG53832 AK172797 BAD18771 AK225942 AK313168 BAG35986 BC001698 AAH01698 DA266414 XM_005265334 XP_005265391 XM_005265335 XP_005265392 XM_005265336 XP_005265393 NM_020676 NP_065727
Function Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:22969151). Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). {ECO:0000250|UniProtKB:Q8R2Y0, ECO:0000269|PubMed:22969151}.
Subcellular Location Membrane {ECO:0000250|UniProtKB:Q8R2Y0}; Single-pass type II membrane protein {ECO:0000255}. Mitochondrion {ECO:0000250|UniProtKB:Q8R2Y0}.
Top Pathways Retrograde endocannabinoid signaling

ABHD6 (G-12) - sc-99255 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ABHD6 antibody - ab87532 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of ABHD6 staining in Human Hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab87532, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-ABHD6 antibody - ab74681 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab74681 at 1/500-1/1000 dilution staining ABHD6 in A549 cells by Immunofluorescence, in the absence (-) or presence (+) of the immunising peptide.

Anti-ABHD6 antibody - ab133855 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ABHD6 antibody (ab133855) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-ABHD6 Antibody (aa231-280) IHC-plus™ - LS-B9707 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ABHD6 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9707 concentration 10 ug/ml.

Anti-ABHD6 Antibody (aa252-265) - LS-C87332 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ABHD6 Antibody - LS-C137428 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABHD6 Antibody (C-Terminus) - LS-C152090 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ABHD6 antibody Western Blot of Fetal Heart.

ABHD6 Antibody - H00057406-B01-50ul from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

ABHD6 Antibody - NBP1-86058 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABHD6 Antibody [NBP1-86058] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY412310)

Anti-ABHD6 antibody produced in rabbit - HPA017283 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ABHD6: <B>Cat. No. HPA017283</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebral cortex shows nuclear membranous positivity in neuronal cells.

Anti-ABHD6 antibody produced in rabbit - SAB4502488 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ABHD6: <B>Cat. No. SAB4502488</B>: Immunofluorescence of A549 cells using Anti-ABHD6 antibody. Cells on the left were treated with the Anti-ABHD6 antibody. Cells on the right (negative control) were treated with both Anti-ABHD6 antibody and the synthesized immunogen peptide.

ABHD6 Antibody - C-terminal region (ARP65850_P050) - ARP65850_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABHD6-Antibody-internal-region - AF2809a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ABHD6 antibody - GTX87697 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-ABHD6 antibody used in ICC/IF. GTX87697

ABHD6 antibody, Internal - GTX88635 from GeneTex

Prices $239.00
Sizes 100 μg
Host Goat
Clonality Polyclonal

ABHD6 Antibody (OAAF03213) - OAAF03213 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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