FGG

Gene Symbol FGG
Entrez Gene 2266
Alt Symbol -
Species Human
Gene Type protein-coding
Description fibrinogen gamma chain
Other Description fibrinogen, gamma polypeptide
Swissprots Q9UC62 Q96A14 Q9UC63 Q9UCF3 A8K057 Q53Y18 P02679 P04470 P04469 Q96KJ3
Accessions AAA52430 AAA52431 AAB59530 AAB59531 AAK19751 AAK19752 CDL78904 EAX04905 EAX04906 EAX04907 EAX04908 EAX04909 EAX04910 EAX04911 EAX04912 EAX04913 EAX04914 EAX04915 EAX04916 EAX04917 EAX04918 EAX04919 EAX04920 EAX04921 EAX04922 EAX04923 P02679 AA936960 AI808530 AK289422 BAF82111 AK290824 BAF83513 AL531173 BC007044 AAH07044 BC021674 AAH21674 BG567044 BT007081 AAP35744 BX538098 CAD98014 X00086 CAA24944 X51473 CAA35837 NM_000509 NP_000500 NM_021870 NP_068656
Function Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection

Fibrinogen γ (B-1) - sc-133157 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibrinogen γ (B-1): sc-133157. Western blot analysis of Fibrinogen γ expression human platelet extract (A), rat PBL whole cell lysate (B) and HeLa nuclear extract (C).

Fibrinogen γ (2.G2.H9) - sc-81620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibrinogen γ (2.G2.H9): sc-81620. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing cytoplasmic staining of ovarian stroma cells and endothelial cells and extracellular staining of plasma.

Fibrinogen γ (C-20) - sc-18032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Fibrinogen γ (C-20): sc-18032. Western blot analysis of purified human Fibrinogen γ (A) and Fibrinogen γ expression in human platelet extracts (B).

Fibrinogen γ (D-6) - sc-133226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibrinogen γ (D-6): sc-133226. Western blot analysis of Fibrinogen γ expression in human platelet extract (A), human PBL (B) and mouse PBL (C) whole cell lysates.

Fibrinogen γ (G-10) - sc-133156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibrinogen γ (G-10): sc-133156. Western blot analysis of Fibrinogen γ expression human platelet extract.

Fibrinogen γ (G-20) - sc-18031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Fibrinogen γ (H-194) - sc-33582 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Fibrinogen γ (H-194): sc-33582. Western blot analysis of Fibrinogen γ expression mouse PBL whole cell lysate.

Anti-Fibrinogen gamma chain antibody - ab137728 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Fibrinogen gamma chain antibody (ab137728) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Fibrinogen gamma chain antibody - ab96532 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Fibrinogen gamma chain antibody (ab96532) at 1/1000 dilution (10% SDS PAGE) + MOLT4 whole cell lysate at 30 µg

Anti-Fibrinogen gamma chain antibody - ab86579 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Fibrinogen gamma chain antibody (ab86579) at 1/50 dilution + NCI-H460 cell line lysate at 35 µg

Anti-Fibrinogen gamma chain antibody [1F2] - ab117616 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
Anti-Fibrinogen gamma chain antibody [1F2] (ab117616) at 1/500 dilution + HeLa nuclear extract

Anti-Fibrinogen gamma chain antibody [5A6] - ab119948 from Abcam

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A6
Anti-Fibrinogen gamma chain antibody [5A6] (ab119948) at 1/500 dilution + Recombinant Fibrinogen gamma chain protein

Anti-Fibrinogen gamma chain antibody [EPR3084] - ab92481 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3084
Anti-Fibrinogen gamma chain antibody [EPR3084] (ab92481) at 1/500 dilution + Human plasma lysate at 10 µgSecondaryHRP labelled goat anti-rabbit IgG at 1/2000 dilution

Anti-Fibrinogen gamma chain antibody [EPR3085] - ab133339 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3085
Anti-Fibrinogen gamma chain antibody [EPR3085] (ab133339) at 1/1000 dilution + Human plasma cell lysate at 10 µgSecondaryGoat Anti-rabbit HRP at 1/2000 dilution

Anti-Fibrinogen gamma chain antibody [EPSISR41] - ab171748 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPSISR41
All lanes : Anti-Fibrinogen gamma chain antibody [EPSISR41] (ab171748) at 1/1000 dilutionLane 1 : Human serum lysateLane 2 : Human plasma lysateLysates/proteins at 10 µg per lane.

Anti-FGG / Fibrinogen Gamma Antibody (aa27-435) - LS-C293880 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant FGG / Fibrinogen Gamma.

Anti-FGG / Fibrinogen Gamma Antibody (aa170-429, FITC) - LS-C304444 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FGG / Fibrinogen Gamma Antibody (aa168-405, FITC) - LS-C303949 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FGG / Fibrinogen Gamma Antibody (aa168-405) - LS-C293881 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant FGG / Fibrinogen Gamma.

Anti-FGG / Fibrinogen Gamma Antibody (clone 5A6) - LS-C169416 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A6
Immunofluorescence of NIH/3T3 cells using FGG mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Anti-FGG / Fibrinogen Gamma Antibody - LS-C334184 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using FGG antibody.

Anti-FGG / Fibrinogen Gamma Antibody (aa417-445) - LS-C100912 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FGG Antibody (RB18714) IHC of formalin-fixed and paraffin-embedded human hepatocarcinoma tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-FGG / Fibrinogen Gamma Antibody (clone 1C1) - LS-C338373 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGG (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGG.

Anti-FGG / Fibrinogen Gamma Antibody (aa216-265) IHC-plus™ - LS-B6833 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FGG / Fibrinogen Gamma Chain antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6833 concentration 5 ug/ml.

Anti-FGG / Fibrinogen Gamma Antibody (clone 2B6) - LS-C338376 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGG (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGG.
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