| Gene Symbol |
Fgf4
|
| Entrez Gene |
14175
|
| Alt Symbol |
Fgf-4, Fgfk, Hst1, Hstf-1, KS3, hst, hst-1, kFGF
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
fibroblast growth factor 4
|
| Other Description |
HBGF-4|K-fibroblast growth factor|heparin-binding growth factor 4
|
| Swissprots |
P15657 Q542N0 P11403
|
| Accessions |
CAA32967 EDL18271 P11403 AK082814 BAC38631 BC104312 AAI04313 BC104313 AAI04314 M30642 AAA37619 XM_011241981 XP_011240283 NM_010202 NP_034332
|
| Function |
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Is essential for survival of the postimplantation mouse embryo. Required for normal limb and cardiac valve development during embryogenesis.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Expressed in the blastocyst inner cell mass and later in distinct embryonic tissues.
|
| Top Pathways |
Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton
|