ALMS1

Gene Symbol	ALMS1
Entrez Gene	7840
Alt Symbol	ALSS
Species	Human
Gene Type	protein-coding
Description	Alstrom syndrome protein 1
Other Description	Alstrom syndrome 1
Swissprots	Q8TCU4 Q53S05 Q9Y4G4 Q86VP9 Q580Q8
Accessions	AAX82023 AAY24208 AJF45347 EAW99728 EAW99729 EAW99730 EAW99731 Q8TCU4 AB002326 BAA20786 AJ417593 CAD10391 AL832273 AL833495 AX751581 CAE11759 BC035025 AAH35025 BC050330 AAH50330 BX647706 BX648632 EF151141 ABL96615 NM_015120 NP_055935
Function	Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells. {ECO:0000269|PubMed:17954613}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with centrosomes and basal bodies at the base of primary cilia. Specifically locates to the proximal ends of centrioles and basal bodies. Colocalizes partially with NCAPD2 at these sites. During mitosis localizes to both spindle poles.
Tissue Specificity	Expressed in all tissues tested including adipose and pancreas. Expressed by beta-cells of the islets in the pancreas (at protein level). {ECO:0000269|PubMed:11941369, ECO:0000269|PubMed:11941370}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

ALMS1 CRISPR/Cas9 KO Plasmid (h) - sc-407355 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 HDR Plasmid (h) - sc-407355-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 Double Nickase Plasmid (h) - sc-407355-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 Double Nickase Plasmid (h2) - sc-407355-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 CRISPR Activation Plasmid (h) - sc-407355-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 CRISPR Activation Plasmid (h2) - sc-407355-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 Lentiviral Activation Particles (h) - sc-407355-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 Lentiviral Activation Particles (h2) - sc-407355-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 siRNA (h) - sc-72345 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ALMS1 shRNA Plasmid (h) - sc-72345-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ALMS1 shRNA (h) Lentiviral Particles - sc-72345-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU006471 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3075 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3075 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02786 from Sigma-Aldrich Category miRNA

ALMS1 siRNA (Human) - CRH5289 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ALMS1 - MBS8239262 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ALMS1 (NM_015120.4) - SHH235318 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ALMS1(NM_015120.4) - SHG031753 from Creative biogene Category siRNA Species Reactivities Human

ALMS1 CRISPR/Cas9 KO Plasmid (h2) - sc-407355-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ALMS1 HDR Plasmid (h2) - sc-407355-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human ALMS1 siRNA - orb265791 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ALMS1 shRNA Plasmid (Human) - CHH5289 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ALMS1 miRNA 3'UTR clone - MiUTR1H-00310 from Creative biogene Species Reactivities Human

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