| Gene Symbol |
TUBB2B
|
| Entrez Gene |
347733
|
| Alt Symbol |
PMGYSA, bA506K6.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulin, beta 2B class IIb
|
| Other Description |
class II beta-tubulin isotype|class IIb beta-tubulin|tubulin beta-2B chain|tubulin, beta polypeptide paralog
|
| Swissprots |
A8K068 Q9BVA1
|
| Accessions |
EAW55125 EAW55126 EAW55127 EAW55128 Q9BVA1 AF035316 AAB88188 AK289433 BAF82122 AK297568 BAH12617 AK308806 AL050056 CAB43252 BC001352 AAH01352 BC063610 AAH63610 BC127872 AAI27873 BC127874 AAI27875 BG056085 BT019930 AAV38733 BX419454 CR456788 CAG33069 HQ447903 ADQ32387 XM_011514571 XP_011512873 NM_178012 NP_821080
|
| Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB2B is implicated in neuronal migration. {ECO:0000250, ECO:0000269|PubMed:19465910}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
High expression in brain. {ECO:0000269|PubMed:20191564}.
|
| Top Pathways |
Gap junction, Pathogenic Escherichia coli infection, Phagosome
|