GDF9

Gene Symbol	GDF9
Entrez Gene	2661
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	growth differentiation factor 9
Other Description	GDF-9|growth/differentiation factor 9
Swissprots	Q4VAW5 O60383
Accessions	AAC08450 EAW62309 O60383 AA604716 AK301962 BAG63375 AK315973 BAH14344 BC096228 AAH96228 BC096229 AAH96229 BC096230 AAH96230 BC096231 AAH96231 BX117145 CA488820 DB040027 DB320693 HY015857 HY042819 HY045713 HY211060 XM_005271957 XP_005272014 XM_006714585 XP_006714648 XM_011543308 XP_011541610 XM_011543309 XP_011541611 XM_011543310 XP_011541612 XM_011543311 XP_011541613 NM_001288824 NP_001275753 NM_001288825 NP_001275754 NM_001288826 NP_001275755 NM_001288827 NP_001275756 NM_001288828 NP_001275757 NM_005260 NP_005251
Function	Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. {ECO:0000269|PubMed:12050262, ECO:0000269|PubMed:19366876, ECO:0000269|PubMed:20660033, ECO:0000269|PubMed:21632818, ECO:0000269|PubMed:21829661}.
Subcellular Location	Secreted {ECO:0000250}.
Tissue Specificity	Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level). {ECO:0000269|PubMed:10443672, ECO:0000269|PubMed:12050262}.
Top Pathways	Ovarian steroidogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GDF 9 peptide - ab106422 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human GDF 9 full length protein - ab158509 from Abcam Category Protein Source Wheat germ Species Human

GDF9 / GDF-9 Antibody Blocking Peptide - LS-E1474 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GDF9 / GDF-9 Antibody Blocking Peptide - LS-E6849 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GDF-9 Recombinant Protein - H00002661-P01 from Novus Biologicals Category Protein

GDF-9 Protein - NBP1-99374 from Novus Biologicals Category Protein Prices $309.00 Sizes 20 µg Species Human

GDF-9 Protein - NBP1-99744 from Novus Biologicals Category Protein Species Human

GDF-9 Peptide - P0861 from Novus Biologicals Category Peptide Species Human

GDF9-Antibody-N-term-Blocking-peptide - BP12182a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GDF9-Antibody-N-term-Blocking-Peptide - BP2069a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GDF9 recombinant protein - GTX65104 from GeneTex Category Protein Prices $249.00 Sizes 20 μg Source E. coli Species Human

Recombinant Human GDF-9 - 8266-G9-010 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived, Gly320-Arg454 (Gly391Arg)

Human GDF9 protein - orb244224 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

GDF9 protein - 30R-2742 from Fitzgerald Category Protein Prices $295.00 Sizes 20 µg Source E.coli Species Human

GDF9 Blocking Peptide - abx062662 from Abbexa Category Peptide Species Human

Human GDF9 Protein - abx066952 from Abbexa Category Protein Source E.coli Species Human

GDF9 - H00002661-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Growth Differentiation Factor 9 (GDF9), Human - 20-6664 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Human

GDF9 fusion protein - ag14488 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GDF9 fusion protein - Ag13784 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GDF9 fusion protein - ag13839 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GDF9 fusion protein - ag13861 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Growth Differentiation Factor 9, His-tagged - GDF9-223H from Creative Biomart Category Protein Source E. Coli.

Recombinant Human Growth Differentiation Factor 9 - GDF9-245H from Creative Biomart Category Protein Source E.coli .

Recombinant Human GDF9 - GDF9-999H from Creative Biomart Category Protein Source HEK293 Cells Species Human

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