ATP2B3

Gene Symbol ATP2B3
Entrez Gene 492
Alt Symbol CFAP39, CLA2, OPCA, PMCA3, PMCA3a, SCAX1
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, plasma membrane 3
Other Description cilia and flagella associated protein 39|plasma membrane calcium ATPase|plasma membrane calcium pump|plasma membrane calcium-transporting ATPase 3
Swissprots B7WNR8 B7WNY5 Q12995 Q16858 Q16720
Accessions EAW72858 EAW72859 EAW72860 Q16720 AK090838 AK094500 AK130194 BAC85302 AK307765 AK308705 BC047580 BC130009 AAI30010 BG739902 BM680649 BM695792 BM805938 BM986989 BQ878721 BU183973 BU790224 BU790521 DQ201779 ABG24243 U15689 AAA60986 U15690 AAA60987 U57971 AAB09762 U60414 AAB38530 XM_005274689 XP_005274746 XM_005274690 XP_005274747 XM_005274691 XP_005274748 XM_005274692 XP_005274749 XM_011531174 XP_011529476 XM_011531175 XP_011529477 XM_011531176 XP_011529478 XM_011531177 XP_011529479 NM_001001344 NP_001001344 NM_021949 NP_068768
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in the cerebellum, particulary in the presynaptic terminals of parallel fibers- Purkinje neurons. Isoform XE and isoform XB are the most abundant isoforms and are detected at low levels in brain and fetal skeletal muscle. The other isoforms are only found at lower levels and not in fetal tissues. {ECO:0000269|PubMed:22912398}.
Top Pathways Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

PMCA3 (G-6) - sc-390148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA3 (G-6): sc-390148. Western blot analysis of PMCA3 expression in mouse brain tissue extract.

PMCA3 (C-15) - sc-22076 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PMCA3 (C-15): sc-22076. Western blot analysis of PMCA3 expression in mouse brain (A), mouse cerebellum (B) and rat cerebellum (C) tissue extracts.

PMCA3 (N-18) - sc-22074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Calcium Pump PMCA3 ATPase antibody - ab3530 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab3530 at 1/200 staining rat hippocampal slices and slice cultures by IHC-P. The tissue was paraformaldehyde fixed, permeabilized with Triton X-100 and blocked with BSA before incubating with the antibody for 12 hours. An Alexa Fluor ®488 conjugated goat anti rabbit antibody was used secondary.See Abreview

Anti-ATP2B3 / PMCA3 Antibody (N-Terminus) - LS-C102095 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ATP2B3 / PMCA3 antibody LS-C102095 Western blot of Fetal Heart lysate.

Anti-ATP2B3 / PMCA3 Antibody (aa144-193) - LS-C102096 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ATP2B3 / PMCA3 antibody LS-C102096 Western blot of Placenta lysate.

PMCA3 Antibody - NBP1-59426 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PMCA3 Antibody [NBP1-59426] - Human Heart lysate, concentration 0.2-1 ug/ml.

PMCA3 Antibody - NBP1-87259 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PMCA3 Antibody - NBP2-19871 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PMCA3 Antibody [NBP2-19871] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:1000.

PMCA3 Antibody - NBP1-59465 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PMCA3 Antibody [NBP1-59465] - Human Placenta lysate, concentration 0.2-1 ug/ml.

Anti-ATP2B3 (ab2) antibody produced in rabbit - SAB2100183 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATP2B3 (ab2): <B>Cat. No.SAB2100183</B>: ATP2B3 in Placenta tissue lysate with ATP2B3 antibody at 1.0 μg/mL.

Anti-ATP2B3 (ab1) antibody produced in rabbit - SAB2100182 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATP2B3 (ab1): <B>Cat. No.SAB2100182</B>: ATP2B3 in Fetal Heart tissue lysate with ATP2B3 antibody at 1.0 μg/mL.
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