| Gene Symbol | Tyr |
|---|---|
| Entrez Gene | 22173 |
| Alt Symbol | Oca1, albino, c, skc35 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | tyrosinase |
| Other Description | albino locus protein|monophenol monooxygenase |
| Swissprots | P11344 |
| Accessions | AAG38744 BAA00340 CAA36033 EDL06800 EDL06801 P11344 AK014619 BAB29466 AK148172 BAE28392 AK148341 BAE28494 AK148357 BAE28503 AK148427 AK148432 BAE28551 AY526904 AAS93265 BC079678 AAH79678 D00131 BAA00079 D00440 BAA00341 D84001 M20234 AAA40516 M24560 AAA40517 M26729 AAA37806 X12782 CAA31273 XM_006507576 XP_006507639 XM_006507577 XP_006507640 XM_006507578 XP_006507641 NM_011661 NP_035791 |
| Function | This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. |
| Subcellular Location | Melanosome membrane; Single-pass type I membrane protein. |
| Top Pathways | Melanogenesis, Tyrosine metabolism, Riboflavin metabolism |
C/EBP ζ CRISPR/Cas9 KO Plasmid (m) - sc-419622 from Santa Cruz Biotechnology
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C/EBP ζ HDR Plasmid (m) - sc-419622-HDR from Santa Cruz Biotechnology
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C/EBP ζ Double Nickase Plasmid (m) - sc-419622-NIC from Santa Cruz Biotechnology
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C/EBP ζ Double Nickase Plasmid (m2) - sc-419622-NIC-2 from Santa Cruz Biotechnology
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C/EBP β CRISPR/Cas9 KO Plasmid (m) - sc-419623 from Santa Cruz Biotechnology
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C/EBP β HDR Plasmid (m) - sc-419623-HDR from Santa Cruz Biotechnology
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C/EBP β Double Nickase Plasmid (m) - sc-419623-NIC from Santa Cruz Biotechnology
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C/EBP β Double Nickase Plasmid (m2) - sc-419623-NIC-2 from Santa Cruz Biotechnology
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C/EBP δ CRISPR/Cas9 KO Plasmid (m) - sc-419624 from Santa Cruz Biotechnology
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C/EBP δ HDR Plasmid (m) - sc-419624-HDR from Santa Cruz Biotechnology
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C/EBP δ Double Nickase Plasmid (m) - sc-419624-NIC from Santa Cruz Biotechnology
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C/EBP δ Double Nickase Plasmid (m2) - sc-419624-NIC-2 from Santa Cruz Biotechnology
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C/EBP ε CRISPR/Cas9 KO Plasmid (m) - sc-431048 from Santa Cruz Biotechnology
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C/EBP ε HDR Plasmid (m) - sc-431048-HDR from Santa Cruz Biotechnology
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C/EBP ε Double Nickase Plasmid (m) - sc-431048-NIC from Santa Cruz Biotechnology
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C/EBP ε Double Nickase Plasmid (m2) - sc-431048-NIC-2 from Santa Cruz Biotechnology
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C/EBP ζ CRISPR Activation Plasmid (m) - sc-419622-ACT from Santa Cruz Biotechnology
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C/EBP ζ CRISPR Activation Plasmid (m2) - sc-419622-ACT-2 from Santa Cruz Biotechnology
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C/EBP ζ Lentiviral Activation Particles (m) - sc-419622-LAC from Santa Cruz Biotechnology
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C/EBP ζ Lentiviral Activation Particles (m2) - sc-419622-LAC-2 from Santa Cruz Biotechnology
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C/EBP β CRISPR Activation Plasmid (m) - sc-419623-ACT from Santa Cruz Biotechnology
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C/EBP β CRISPR Activation Plasmid (m2) - sc-419623-ACT-2 from Santa Cruz Biotechnology
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C/EBP β Lentiviral Activation Particles (m) - sc-419623-LAC from Santa Cruz Biotechnology
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C/EBP β Lentiviral Activation Particles (m2) - sc-419623-LAC-2 from Santa Cruz Biotechnology
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C/EBP δ CRISPR Activation Plasmid (m) - sc-419624-ACT from Santa Cruz Biotechnology
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